Mesenchymal stem cells-derived small extracellular vesicles alleviate diabetic retinopathy by delivering NEDD4

Mesenchymal stem cells-derived small extracellular vesicles alleviate diabetic retinopathy by delivering NEDD4

Abstract Background As a leading cause of vision decline and severe blindness in adults, diabetic retinopathy (DR) is characterized by the aggravation of retinal oxidative stress and apoptosis in the early stage. Emerging studies reveal that mesenchymal stem cells-derived small extracellular vesicle...

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Bibliographic Details
Main Authors: Fengtian Sun, Yuntong Sun, Junyan Zhu, Xiaoling Wang, Cheng Ji, Jiahui Zhang, Shenyuan Chen, Yifan Yu, Wenrong Xu, Hui Qian
Format: Article
Language:English
Published: BMC 2022-07-01
Series:Stem Cell Research & Therapy
Subjects:
MSC-sEV
NEDD4
DR
RPE
PTEN
AKT
Online Access:https://doi.org/10.1186/s13287-022-02983-0

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