The efficacy of the oral capsule of aqueous alcoholic extract of red onion on blood sugar of women with gestational diabetes treated with diet

Introduction: Mothers with gestational diabetes and their babies are exposed to significant maternal and neonatal complications. This study was conducted with aim to determine the effect of oral capsule of aqueous alcoholic extract of red onion on blood sugar of women with gestational diabetes treat...

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Main Authors: Farzaneh Salajegheh Tezerji, Roshanak Salari, Seyed Reza Mazloum, Farideh Akhlaghi, Raheleh Babazadeh
Format: Article
Language:fas
Published: Mashhad University of Medical Sciences 2023-08-01
Series:Majallah-i Zanān, Māmā̓ī va Nāzā̓ī-i Īrān
Subjects:
Online Access:https://ijogi.mums.ac.ir/article_23244_203dc78ad70b6782c257e23ae83565ff.pdf
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author Farzaneh Salajegheh Tezerji
Roshanak Salari
Seyed Reza Mazloum
Farideh Akhlaghi
Raheleh Babazadeh
author_facet Farzaneh Salajegheh Tezerji
Roshanak Salari
Seyed Reza Mazloum
Farideh Akhlaghi
Raheleh Babazadeh
author_sort Farzaneh Salajegheh Tezerji
collection DOAJ
description Introduction: Mothers with gestational diabetes and their babies are exposed to significant maternal and neonatal complications. This study was conducted with aim to determine the effect of oral capsule of aqueous alcoholic extract of red onion on blood sugar of women with gestational diabetes treated with diet. Methods: This triple-blind randomized clinical trial study was conducted in 2021-2022 on 60 women with gestational diabetes in Mashhad. Eligible mothers at 24 to 30 weeks of gestation were randomly divided into two groups of 30 people, intervention or placebo, and took 500 mg capsules of red onion extract or placebo twice a day for 4 weeks. Fasting blood sugar was checked before, two weeks and four weeks after the study, and two hours after meals. Data analysis was done using SPSS statistical software (version 16) and Chi-square, Independent t and Mann-Whitney tests. P<0.05 was considered statistically significant. Results: There was a statistically significant difference in the intervention group compared to the placebo group in the mean fasting blood sugar two and four weeks after the study (P<0.05). However, there was no statistically significant difference in the intervention group compared to the placebo group in the mean blood sugar two hours after a meal two and four weeks later compared to before the study (P>0.05). Conclusion: Considering the effect of red onion extract in reducing fasting blood sugar in women with gestational diabetes, it is recommended to teach its use in health centers.
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spelling doaj.art-820fda2dd1594fd8b56cb8152961b3412023-12-07T04:18:28ZfasMashhad University of Medical SciencesMajallah-i Zanān, Māmā̓ī va Nāzā̓ī-i Īrān1680-29932008-23632023-08-01266728210.22038/ijogi.2023.2324423244The efficacy of the oral capsule of aqueous alcoholic extract of red onion on blood sugar of women with gestational diabetes treated with dietFarzaneh Salajegheh Tezerji0Roshanak Salari1Seyed Reza Mazloum2Farideh Akhlaghi3Raheleh Babazadeh4M.Sc. Student of Midwifery, School of Nursing and Midwifery, Mashhad University of Medical Sciences, Mashhad, Iran.Associate Professor, Department of Pharmaceutical Sciences in Persian Medicine, School of Persian and Complementary Medicine, Mashhad University of Medical Sciences, Mashhad, Iran.Instructor, Department of Nursing, Evidence-Based Care Research Center, School of Nursing and Midwifery, Mashhad University of Medical Sciences, Mashhad, Iran.Professor, Department of Obstetrics and Gynecology, Women&#039;s Health Research Center, Faculty of Medicine, Mashhad University of Medical Sciences, Mashhad, Iran.Assistant Professor, Department of Midwifery, Nursing and Midwifery Care Research Center, School of Nursing and Midwifery, Mashhad University of Medical Sciences, Mashhad, Iran.Introduction: Mothers with gestational diabetes and their babies are exposed to significant maternal and neonatal complications. This study was conducted with aim to determine the effect of oral capsule of aqueous alcoholic extract of red onion on blood sugar of women with gestational diabetes treated with diet. Methods: This triple-blind randomized clinical trial study was conducted in 2021-2022 on 60 women with gestational diabetes in Mashhad. Eligible mothers at 24 to 30 weeks of gestation were randomly divided into two groups of 30 people, intervention or placebo, and took 500 mg capsules of red onion extract or placebo twice a day for 4 weeks. Fasting blood sugar was checked before, two weeks and four weeks after the study, and two hours after meals. Data analysis was done using SPSS statistical software (version 16) and Chi-square, Independent t and Mann-Whitney tests. P<0.05 was considered statistically significant. Results: There was a statistically significant difference in the intervention group compared to the placebo group in the mean fasting blood sugar two and four weeks after the study (P<0.05). However, there was no statistically significant difference in the intervention group compared to the placebo group in the mean blood sugar two hours after a meal two and four weeks later compared to before the study (P>0.05). Conclusion: Considering the effect of red onion extract in reducing fasting blood sugar in women with gestational diabetes, it is recommended to teach its use in health centers.https://ijogi.mums.ac.ir/article_23244_203dc78ad70b6782c257e23ae83565ff.pdfblood glucosediet therapygestational diabetesred onion
spellingShingle Farzaneh Salajegheh Tezerji
Roshanak Salari
Seyed Reza Mazloum
Farideh Akhlaghi
Raheleh Babazadeh
The efficacy of the oral capsule of aqueous alcoholic extract of red onion on blood sugar of women with gestational diabetes treated with diet
Majallah-i Zanān, Māmā̓ī va Nāzā̓ī-i Īrān
blood glucose
diet therapy
gestational diabetes
red onion
title The efficacy of the oral capsule of aqueous alcoholic extract of red onion on blood sugar of women with gestational diabetes treated with diet
title_full The efficacy of the oral capsule of aqueous alcoholic extract of red onion on blood sugar of women with gestational diabetes treated with diet
title_fullStr The efficacy of the oral capsule of aqueous alcoholic extract of red onion on blood sugar of women with gestational diabetes treated with diet
title_full_unstemmed The efficacy of the oral capsule of aqueous alcoholic extract of red onion on blood sugar of women with gestational diabetes treated with diet
title_short The efficacy of the oral capsule of aqueous alcoholic extract of red onion on blood sugar of women with gestational diabetes treated with diet
title_sort efficacy of the oral capsule of aqueous alcoholic extract of red onion on blood sugar of women with gestational diabetes treated with diet
topic blood glucose
diet therapy
gestational diabetes
red onion
url https://ijogi.mums.ac.ir/article_23244_203dc78ad70b6782c257e23ae83565ff.pdf
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