Inclusion complex of the antiviral drug acyclovir with cyclodextrin in aqueous solution and in solid phase

Inclusion complex of the antiviral drug acyclovir with cyclodextrin in aqueous solution and in solid phase

Complexation between acyclovir (ACV), an antiviral drug used for the treatment of herpes simplex virus infection, and beta-cyclodextrin (beta-CD) was studied in solution and in solid states. Complexation in solution was evaluated using solubility studies and nuclear magnetic resonance spectroscopy (...

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Bibliographic Details
Main Authors: Carlos von Plessing Rossel, Jacqueline Sepúlveda Carreño, Mario Rodríguez-Baeza, Joel Bernabé Alderete
Format: Article
Language:English
Published: Sociedade Brasileira de Química 2000-12-01
Series:Química Nova
Subjects:
cyclodextrin
acyclovir
inclusion complex
Online Access:http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-40422000000600007

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