The presence of Plasmodium malariae and Plasmodium knowlesi in near malaria elimination setting in western Indonesia
Abstract Background Indonesia is progressing towards malaria elimination. To achieve this goal, intervention measures must be addressed to cover all Plasmodium species. Comprehensive control measures and surveillance programmes must be intensified. This study aims to determine the prevalence of micr...
| Main Authors: | , , , , , , , , , , |
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| Format: | Article |
| Language: | English |
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BMC
2022-11-01
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| Series: | Malaria Journal |
| Subjects: | |
| Online Access: | https://doi.org/10.1186/s12936-022-04335-y |
| _version_ | 1797984679280771072 |
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| author | Irbah Rea Alvieda Nainggolan Rycha Dwi Syafutri Monica Nadya Sinambela Clara Devina Handayani Beby Syofiani Hasibuan Sriwipa Chuangchaiya Paul C. S. Divis Zulkarnain Md Idris Ranti Permatasari Inke Nadia Diniyanti Lubis |
| author_facet | Irbah Rea Alvieda Nainggolan Rycha Dwi Syafutri Monica Nadya Sinambela Clara Devina Handayani Beby Syofiani Hasibuan Sriwipa Chuangchaiya Paul C. S. Divis Zulkarnain Md Idris Ranti Permatasari Inke Nadia Diniyanti Lubis |
| author_sort | Irbah Rea Alvieda Nainggolan |
| collection | DOAJ |
| description | Abstract Background Indonesia is progressing towards malaria elimination. To achieve this goal, intervention measures must be addressed to cover all Plasmodium species. Comprehensive control measures and surveillance programmes must be intensified. This study aims to determine the prevalence of microscopic and submicroscopic malaria in Langkat district, North Sumatera Province, Indonesia. Methods A cross-sectional survey was conducted in six villages in Langkat district, North Sumatera Province in June 2019. Data were recorded using a standardized questionnaire. Finger pricked blood samples were obtained for malaria examination using rapid diagnostic test, thick and thin blood smears, and polymerase chain reaction. Results A total of 342 individuals were included in the study. Of them, one (0.3%) had a microscopic Plasmodium malariae infection, no positive RDT examination, and three (0.9%) were positive for P. malariae (n = 1) and Plasmodium knowlesi (n = 2). The distribution of bed net ownership was owned by 40% of the study participants. The participants had a house within a radius of 100–500 m from the forest (86.3%) and had the housing material of cement floor (56.1%), a tin roof (82.2%), wooden wall (35.7%), bamboo wall (28.1%), and brick wall (21.6%). Conclusion Malaria incidence has substantially decreased in Langkat, North Sumatera, Indonesia. However, submicroscopic infection remains in the population and may contribute to further transmission. Surveillance should include the detection of microscopic undetected parasites, to enable the achievement of malaria elimination. |
| first_indexed | 2024-04-11T07:05:50Z |
| format | Article |
| id | doaj.art-8213c8d035d9432d86b7911a00870e08 |
| institution | Directory Open Access Journal |
| issn | 1475-2875 |
| language | English |
| last_indexed | 2024-04-11T07:05:50Z |
| publishDate | 2022-11-01 |
| publisher | BMC |
| record_format | Article |
| series | Malaria Journal |
| spelling | doaj.art-8213c8d035d9432d86b7911a00870e082022-12-22T04:38:23ZengBMCMalaria Journal1475-28752022-11-012111710.1186/s12936-022-04335-yThe presence of Plasmodium malariae and Plasmodium knowlesi in near malaria elimination setting in western IndonesiaIrbah Rea Alvieda Nainggolan0Rycha Dwi Syafutri1Monica Nadya Sinambela2Clara Devina3Handayani4Beby Syofiani Hasibuan5Sriwipa Chuangchaiya6Paul C. S. Divis7Zulkarnain Md Idris8Ranti Permatasari9Inke Nadia Diniyanti Lubis10Faculty of Medicine, Universitas Sumatera UtaraFaculty of Medicine, Universitas Sumatera UtaraFaculty of Medicine, Universitas Sumatera UtaraDepartment of Paediatrics, Faculty of Medicine, Universitas Sumatera UtaraDepartment of Paediatrics, Faculty of Medicine, Universitas Sumatera UtaraDepartment of Paediatrics, Faculty of Medicine, Universitas Sumatera UtaraDepartment of Community Health, Faculty of Public Health, Kasetsart University, Chalermphrakiat Sakon Nakhon Province CampusMalaria Research Centre, Faculty of Medicine and Health Sciences, Universiti Malaysia SarawakDepartment of Parasitology and Medical Entomology, Faculty of Medicine, Universiti Kebangsaan MalaysiaDepartment of Clinical Pathology, Faculty of Medicine, Universitas Sumatera UtaraDepartment of Paediatrics, Faculty of Medicine, Universitas Sumatera UtaraAbstract Background Indonesia is progressing towards malaria elimination. To achieve this goal, intervention measures must be addressed to cover all Plasmodium species. Comprehensive control measures and surveillance programmes must be intensified. This study aims to determine the prevalence of microscopic and submicroscopic malaria in Langkat district, North Sumatera Province, Indonesia. Methods A cross-sectional survey was conducted in six villages in Langkat district, North Sumatera Province in June 2019. Data were recorded using a standardized questionnaire. Finger pricked blood samples were obtained for malaria examination using rapid diagnostic test, thick and thin blood smears, and polymerase chain reaction. Results A total of 342 individuals were included in the study. Of them, one (0.3%) had a microscopic Plasmodium malariae infection, no positive RDT examination, and three (0.9%) were positive for P. malariae (n = 1) and Plasmodium knowlesi (n = 2). The distribution of bed net ownership was owned by 40% of the study participants. The participants had a house within a radius of 100–500 m from the forest (86.3%) and had the housing material of cement floor (56.1%), a tin roof (82.2%), wooden wall (35.7%), bamboo wall (28.1%), and brick wall (21.6%). Conclusion Malaria incidence has substantially decreased in Langkat, North Sumatera, Indonesia. However, submicroscopic infection remains in the population and may contribute to further transmission. Surveillance should include the detection of microscopic undetected parasites, to enable the achievement of malaria elimination.https://doi.org/10.1186/s12936-022-04335-yMalariaIndonesiaNorth SumateraEliminationP. knowlesiP. malariae |
| spellingShingle | Irbah Rea Alvieda Nainggolan Rycha Dwi Syafutri Monica Nadya Sinambela Clara Devina Handayani Beby Syofiani Hasibuan Sriwipa Chuangchaiya Paul C. S. Divis Zulkarnain Md Idris Ranti Permatasari Inke Nadia Diniyanti Lubis The presence of Plasmodium malariae and Plasmodium knowlesi in near malaria elimination setting in western Indonesia Malaria Journal Malaria Indonesia North Sumatera Elimination P. knowlesi P. malariae |
| title | The presence of Plasmodium malariae and Plasmodium knowlesi in near malaria elimination setting in western Indonesia |
| title_full | The presence of Plasmodium malariae and Plasmodium knowlesi in near malaria elimination setting in western Indonesia |
| title_fullStr | The presence of Plasmodium malariae and Plasmodium knowlesi in near malaria elimination setting in western Indonesia |
| title_full_unstemmed | The presence of Plasmodium malariae and Plasmodium knowlesi in near malaria elimination setting in western Indonesia |
| title_short | The presence of Plasmodium malariae and Plasmodium knowlesi in near malaria elimination setting in western Indonesia |
| title_sort | presence of plasmodium malariae and plasmodium knowlesi in near malaria elimination setting in western indonesia |
| topic | Malaria Indonesia North Sumatera Elimination P. knowlesi P. malariae |
| url | https://doi.org/10.1186/s12936-022-04335-y |
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