Reduced Fibroblast Activation on Electrospun Polycaprolactone Scaffolds

Reduced Fibroblast Activation on Electrospun Polycaprolactone Scaffolds

In vivo, quiescent fibroblasts reside in three-dimensional connective tissues and are activated in response to tissue injury before proliferating rapidly and becoming migratory and contractile myofibroblasts. When deregulated, chronic activation drives fibrotic disease. Fibroblasts cultured on stiff...

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Bibliographic Details
Main Authors: Joe P. Woodley, Daniel W. Lambert, Ilida Ortega Asencio
Format: Article
Language:English
Published: MDPI AG 2023-03-01
Series:Bioengineering
Subjects:
fibroblast
3D cell culture
biomaterials
electrospinning
scaffold
Online Access:https://www.mdpi.com/2306-5354/10/3/348

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