Administration of autologous platelet rich plasma and the impact on outcomes of assisted reproduction treatment in infertile women
Objective: There are diverse findings concerning the use of platelet-rich plasma (PRP) in assisted reproduction treatment (ART) cycles of infertile women with low ovarian reserve, ovarian failure or implantation failure due to endometrial problems. A debate continues regarding the benefit of this te...
Main Authors: | , , |
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Format: | Article |
Language: | English |
Published: |
IMR Press
2021-10-01
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Series: | Clinical and Experimental Obstetrics & Gynecology |
Subjects: | |
Online Access: | https://www.imrpress.com/journal/CEOG/48/5/10.31083/j.ceog4805165 |
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author | Pelin Kutlu Seda Karabulut Oya Korkmaz |
author_facet | Pelin Kutlu Seda Karabulut Oya Korkmaz |
author_sort | Pelin Kutlu |
collection | DOAJ |
description | Objective: There are diverse findings concerning the use of platelet-rich plasma (PRP) in assisted reproduction treatment (ART) cycles of infertile women with low ovarian reserve, ovarian failure or implantation failure due to endometrial problems. A debate continues regarding the benefit of this technique because of the low number of evidence-based studies. Mechanism: Different PRP preparation methods have been described in the literature, aiming to obtain the highest number of platelets following centrifugation steps. Findings in brief: Research on the use of PRP in female infertility aims to improve the deteriorated hormonal profile, gamete production and implantation of the embryo into the endometrium. Conclusions: This paper reviewed literature evaluating the impact of PRP on the outcomes of subsequent ART cycles in infertile women. PRP is a safe and easy-to-apply procedure and can be used as an ’add-on’ therapy in patients with reduced ovarian reserve, ovarian failure or implantation failure prior to the in vitro fertilization (IVF) cycle, although it is still regarded as an empirical treatment method. Further studies should be conducted to enlighten the subject. |
first_indexed | 2024-04-12T15:15:24Z |
format | Article |
id | doaj.art-821471301c2f4215b7228b05e037f211 |
institution | Directory Open Access Journal |
issn | 0390-6663 |
language | English |
last_indexed | 2024-04-12T15:15:24Z |
publishDate | 2021-10-01 |
publisher | IMR Press |
record_format | Article |
series | Clinical and Experimental Obstetrics & Gynecology |
spelling | doaj.art-821471301c2f4215b7228b05e037f2112022-12-22T03:27:38ZengIMR PressClinical and Experimental Obstetrics & Gynecology0390-66632021-10-014851025103110.31083/j.ceog4805165S0390-6663(21)00005-1Administration of autologous platelet rich plasma and the impact on outcomes of assisted reproduction treatment in infertile womenPelin Kutlu0Seda Karabulut1Oya Korkmaz2Istanbul Medicana Çamlıca Hospital, IVF Center, 34692 İstanbul, TurkeyDepartment of Histology and Embryology, School of Medicine, Istanbul Medipol University, 34815 İstanbul, TurkeyDepartment of Histology and Embryology, School of Medicine, Istanbul Medipol University, 34815 İstanbul, TurkeyObjective: There are diverse findings concerning the use of platelet-rich plasma (PRP) in assisted reproduction treatment (ART) cycles of infertile women with low ovarian reserve, ovarian failure or implantation failure due to endometrial problems. A debate continues regarding the benefit of this technique because of the low number of evidence-based studies. Mechanism: Different PRP preparation methods have been described in the literature, aiming to obtain the highest number of platelets following centrifugation steps. Findings in brief: Research on the use of PRP in female infertility aims to improve the deteriorated hormonal profile, gamete production and implantation of the embryo into the endometrium. Conclusions: This paper reviewed literature evaluating the impact of PRP on the outcomes of subsequent ART cycles in infertile women. PRP is a safe and easy-to-apply procedure and can be used as an ’add-on’ therapy in patients with reduced ovarian reserve, ovarian failure or implantation failure prior to the in vitro fertilization (IVF) cycle, although it is still regarded as an empirical treatment method. Further studies should be conducted to enlighten the subject.https://www.imrpress.com/journal/CEOG/48/5/10.31083/j.ceog4805165infertilityivfplatelet-rich plasma (prp)ovarian failure |
spellingShingle | Pelin Kutlu Seda Karabulut Oya Korkmaz Administration of autologous platelet rich plasma and the impact on outcomes of assisted reproduction treatment in infertile women Clinical and Experimental Obstetrics & Gynecology infertility ivf platelet-rich plasma (prp) ovarian failure |
title | Administration of autologous platelet rich plasma and the impact on outcomes of assisted reproduction treatment in infertile women |
title_full | Administration of autologous platelet rich plasma and the impact on outcomes of assisted reproduction treatment in infertile women |
title_fullStr | Administration of autologous platelet rich plasma and the impact on outcomes of assisted reproduction treatment in infertile women |
title_full_unstemmed | Administration of autologous platelet rich plasma and the impact on outcomes of assisted reproduction treatment in infertile women |
title_short | Administration of autologous platelet rich plasma and the impact on outcomes of assisted reproduction treatment in infertile women |
title_sort | administration of autologous platelet rich plasma and the impact on outcomes of assisted reproduction treatment in infertile women |
topic | infertility ivf platelet-rich plasma (prp) ovarian failure |
url | https://www.imrpress.com/journal/CEOG/48/5/10.31083/j.ceog4805165 |
work_keys_str_mv | AT pelinkutlu administrationofautologousplateletrichplasmaandtheimpactonoutcomesofassistedreproductiontreatmentininfertilewomen AT sedakarabulut administrationofautologousplateletrichplasmaandtheimpactonoutcomesofassistedreproductiontreatmentininfertilewomen AT oyakorkmaz administrationofautologousplateletrichplasmaandtheimpactonoutcomesofassistedreproductiontreatmentininfertilewomen |