| Summary: | Objective: The aim of the study was to evaluate cognitive functioning in adult women with low level vitamin D and to investigate the relationship between vitamin D and cognitive functioning.
Materials and Methods: Seventy-one women patients aged 18-50 with 25-OH vitamin D3 level <30 ng/mL referred to outpatient clinic were enrolled in the study. 25-OH vitamin D3 level, calcium, phosphate, alkaline phosphatase, parathyroid hormone (PTH) blood levels were studied in all the patients. Mini Mental State Examination (MMSE) and Montreal Cognitive Assessment (MOCA) were used to assess cognitive functioning. The patients were divided into 2 groups according to vitamin D levels: <10 ng/mL (group 1, n=34) and between 11-29 ng/mL (group 2, n=37).
Results: There was no significant difference between the group 1 and 2 for demographic and clinical characteristics except for vitamin D and PTH (p>0.05). Patients in group 1 had their vitamin D levels significantly lower and PTH levels higher than group 2 (p<0.05). There was no significant difference in MOCA and MMSE scores between the groups (p>0.05). Although there was a relationship between education and MOCA and MMSE scores, we didn’t find any significant relationship between age and vitamin D levels and MOCA and MMSE scores.
Conclusion: Although approximately 50% of adult women whose vitamin D levels were low had reduced cognitive function, there was no relationship between vitamin D levels and cognitive functions.
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