Comparison of adenosine deaminase, zinc, magnesium, lipid profile, and some micronutrient elements and their relation with CD4 counts in human immunodeficiency virus positive and negative patients
Background: There is strong evidence regarding the patterns of alteration in the blood parameters in human immunodeficiency virus (HIV)-positive patients. However, no consensus has been reached in this regard and the results vary from different regions and studies. Our study aims to report these pat...
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| Format: | Article |
| Language: | English |
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Wolters Kluwer Medknow Publications
2012-01-01
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| Series: | Journal of Global Infectious Diseases |
| Subjects: | |
| Online Access: | http://www.jgid.org/article.asp?issn=0974-777X;year=2012;volume=4;issue=4;spage=199;epage=206;aulast=Abdollahi |
| _version_ | 1818928956872589312 |
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| author | Alireza Abdollahi Saeed Shoar |
| author_facet | Alireza Abdollahi Saeed Shoar |
| author_sort | Alireza Abdollahi |
| collection | DOAJ |
| description | Background: There is strong evidence regarding the patterns of alteration in the blood parameters in human immunodeficiency
virus (HIV)-positive patients. However, no consensus has been reached in this regard and the results vary from different regions and studies. Our study aims to report these patterns in a population of HIV-infected patients in Iran. Materials and Methods: We studied two groups of HIV-infected and HIV-negative patients. One hundred and fourteen subjects were enrolled in each group; blood parameters were compared in these two. Results: Variables of HIV-negative patients changed as follows compared to HIV-positive patients: with regard to the hematological variables, CD4+↓; CD8+↓; WBC↓; RBC↓; HCT↓ ; MCV↑ ; MCH↑; MCHC↑; PLT↓; EOS↑; and BASO↑; and among the metabloic parameters, TG↓; CH↑; HDL↓; LDL↓, MG↑; ZN↑; P↑; and ADA↓, which showed significnat differences between groups (P < 0.05). Conclusion: We conclude that HIV infection affects hematopoiesis by diminishing the hematological productivity parameters and increasing red blood cell related morphology, along with a different pattern of lipid profile (decreased TG, LDL, HDL, and increased CH) and serum micronutrients (elevated concentration of serum trace elements) in our population of study. |
| first_indexed | 2024-12-20T03:37:09Z |
| format | Article |
| id | doaj.art-821971d5a4c645d69fbbbb70b63df20f |
| institution | Directory Open Access Journal |
| issn | 0974-777X |
| language | English |
| last_indexed | 2024-12-20T03:37:09Z |
| publishDate | 2012-01-01 |
| publisher | Wolters Kluwer Medknow Publications |
| record_format | Article |
| series | Journal of Global Infectious Diseases |
| spelling | doaj.art-821971d5a4c645d69fbbbb70b63df20f2022-12-21T19:54:51ZengWolters Kluwer Medknow PublicationsJournal of Global Infectious Diseases0974-777X2012-01-014419920610.4103/0974-777X.103897Comparison of adenosine deaminase, zinc, magnesium, lipid profile, and some micronutrient elements and their relation with CD4 counts in human immunodeficiency virus positive and negative patientsAlireza AbdollahiSaeed ShoarBackground: There is strong evidence regarding the patterns of alteration in the blood parameters in human immunodeficiency virus (HIV)-positive patients. However, no consensus has been reached in this regard and the results vary from different regions and studies. Our study aims to report these patterns in a population of HIV-infected patients in Iran. Materials and Methods: We studied two groups of HIV-infected and HIV-negative patients. One hundred and fourteen subjects were enrolled in each group; blood parameters were compared in these two. Results: Variables of HIV-negative patients changed as follows compared to HIV-positive patients: with regard to the hematological variables, CD4+↓; CD8+↓; WBC↓; RBC↓; HCT↓ ; MCV↑ ; MCH↑; MCHC↑; PLT↓; EOS↑; and BASO↑; and among the metabloic parameters, TG↓; CH↑; HDL↓; LDL↓, MG↑; ZN↑; P↑; and ADA↓, which showed significnat differences between groups (P < 0.05). Conclusion: We conclude that HIV infection affects hematopoiesis by diminishing the hematological productivity parameters and increasing red blood cell related morphology, along with a different pattern of lipid profile (decreased TG, LDL, HDL, and increased CH) and serum micronutrients (elevated concentration of serum trace elements) in our population of study.http://www.jgid.org/article.asp?issn=0974-777X;year=2012;volume=4;issue=4;spage=199;epage=206;aulast=AbdollahiAdenosine deaminaseHIVMagnesiumZinc |
| spellingShingle | Alireza Abdollahi Saeed Shoar Comparison of adenosine deaminase, zinc, magnesium, lipid profile, and some micronutrient elements and their relation with CD4 counts in human immunodeficiency virus positive and negative patients Journal of Global Infectious Diseases Adenosine deaminase HIV Magnesium Zinc |
| title | Comparison of adenosine deaminase, zinc, magnesium, lipid profile, and some micronutrient elements and their relation with CD4 counts in human immunodeficiency virus positive and negative patients |
| title_full | Comparison of adenosine deaminase, zinc, magnesium, lipid profile, and some micronutrient elements and their relation with CD4 counts in human immunodeficiency virus positive and negative patients |
| title_fullStr | Comparison of adenosine deaminase, zinc, magnesium, lipid profile, and some micronutrient elements and their relation with CD4 counts in human immunodeficiency virus positive and negative patients |
| title_full_unstemmed | Comparison of adenosine deaminase, zinc, magnesium, lipid profile, and some micronutrient elements and their relation with CD4 counts in human immunodeficiency virus positive and negative patients |
| title_short | Comparison of adenosine deaminase, zinc, magnesium, lipid profile, and some micronutrient elements and their relation with CD4 counts in human immunodeficiency virus positive and negative patients |
| title_sort | comparison of adenosine deaminase zinc magnesium lipid profile and some micronutrient elements and their relation with cd4 counts in human immunodeficiency virus positive and negative patients |
| topic | Adenosine deaminase HIV Magnesium Zinc |
| url | http://www.jgid.org/article.asp?issn=0974-777X;year=2012;volume=4;issue=4;spage=199;epage=206;aulast=Abdollahi |
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