Structure-function relationship of substituted bromomethylcoumarins in nucleoside specificity of RNA alkylation.

Structure-function relationship of substituted bromomethylcoumarins in nucleoside specificity of RNA alkylation.

Selective alkylation of RNA nucleotides is an important field of RNA biochemistry, e.g. in applications of fluorescent labeling or in structural probing experiments, yet detailed structure-function studies of labeling agents are rare. Here, bromomethylcoumarins as reactive compounds for fluorescent...

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Bibliographic Details
Main Authors: Stefanie Kellner, Laura Bettina Kollar, Antonia Ochel, Manjunath Ghate, Mark Helm
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/23844135/pdf/?tool=EBI

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