Modulation of B cell activation by extracellular vesicles and potential alteration of this pathway in patients with rheumatoid arthritis

Modulation of B cell activation by extracellular vesicles and potential alteration of this pathway in patients with rheumatoid arthritis

Abstract Background Extracellular vesicles are involved in the intercellular communication of the immune system. In rheumatoid arthritis (RA), these structures are considered a source of autoantigens that drive proinflammatory responses of innate immune cells. A high concentration of circulating med...

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Bibliographic Details
Main Authors: Héctor Rincón-Arévalo, Catalina Burbano, Laura Atehortúa, Mauricio Rojas, Adriana Vanegas-García, Gloria Vásquez, Diana Castaño
Format: Article
Language:English
Published: BMC 2022-07-01
Series:Arthritis Research & Therapy
Subjects:
B cells
Extracellular vesicles
Rheumatoid arthritis
B cell activation
Immune complexes
Autoimmunity
Online Access:https://doi.org/10.1186/s13075-022-02837-3

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