EXPERIENCE WITH RAPTEN RAPID USING IN THE TREATMENT OF ARTICULAR SYNDROME IN RHEUMATOID ARTHRITIS
Summary Our aim was to study the clinical efjicacy of Rapten rapid, its effect on the activity of inflammatory process, parameters of immunity in rheumatoid arthritis as compared with other widely used NSAIDs: sodium diclofenac, Indometacin, Ibuprofen and also to clarify the mechanism of action of a...
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| Format: | Article |
| Language: | Russian |
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IMA PRESS LLC
2001-04-01
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| Series: | Научно-практическая ревматология |
| Subjects: | |
| Online Access: | https://rsp.mediar-press.net/rsp/article/view/535 |
| _version_ | 1797863063605477376 |
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| author | A. B. Zborovsky B V Zavodovsky L L Derevianko |
| author_facet | A. B. Zborovsky B V Zavodovsky L L Derevianko |
| author_sort | A. B. Zborovsky |
| collection | DOAJ |
| description | Summary Our aim was to study the clinical efjicacy of Rapten rapid, its effect on the activity of inflammatory process, parameters of immunity in rheumatoid arthritis as compared with other widely used NSAIDs: sodium diclofenac, Indometacin, Ibuprofen and also to clarify the mechanism of action of above drugs. The study included 110 RA patients which were divided into 4 groups. Pts of the I s' group toolc Rapten rapid (n=50), 2 ml - sodium diclofenac (n—20), 3d - Indometacin (n—20), 4' h - Ibuprofen (n—20). Al the result of the study it was found that Rapten rapid effectively reduces pain syndrome in rheumatoid arthritis, does not give preference to other anti-inflammatory drugs on analgetic and anti-inflammatory effect, has positive influence on laboratory indices of inflammation rendering thus more speedy analgetic effect demonstrated averagely 2 days faster as compared with other NSAJDs. Frequency of side-effects during Rapten rapid application does not reliably differ from other NSAIDs. Rapten rapid possesses immunomodulatory effect demonstrated by decreasing the level of serum IgA, activity of 5‘nucleotidase in lymphocytes, neutrophils, monocytes and myeloperoxidase in monocytes. |
| first_indexed | 2024-04-09T22:29:35Z |
| format | Article |
| id | doaj.art-821f1615b38140828f3224ea43b8bb54 |
| institution | Directory Open Access Journal |
| issn | 1995-4484 1995-4492 |
| language | Russian |
| last_indexed | 2024-04-09T22:29:35Z |
| publishDate | 2001-04-01 |
| publisher | IMA PRESS LLC |
| record_format | Article |
| series | Научно-практическая ревматология |
| spelling | doaj.art-821f1615b38140828f3224ea43b8bb542023-03-22T13:45:37ZrusIMA PRESS LLCНаучно-практическая ревматология1995-44841995-44922001-04-01392374210.14412/1995-4484-2001-397475EXPERIENCE WITH RAPTEN RAPID USING IN THE TREATMENT OF ARTICULAR SYNDROME IN RHEUMATOID ARTHRITISA. B. ZborovskyB V ZavodovskyL L DereviankoSummary Our aim was to study the clinical efjicacy of Rapten rapid, its effect on the activity of inflammatory process, parameters of immunity in rheumatoid arthritis as compared with other widely used NSAIDs: sodium diclofenac, Indometacin, Ibuprofen and also to clarify the mechanism of action of above drugs. The study included 110 RA patients which were divided into 4 groups. Pts of the I s' group toolc Rapten rapid (n=50), 2 ml - sodium diclofenac (n—20), 3d - Indometacin (n—20), 4' h - Ibuprofen (n—20). Al the result of the study it was found that Rapten rapid effectively reduces pain syndrome in rheumatoid arthritis, does not give preference to other anti-inflammatory drugs on analgetic and anti-inflammatory effect, has positive influence on laboratory indices of inflammation rendering thus more speedy analgetic effect demonstrated averagely 2 days faster as compared with other NSAJDs. Frequency of side-effects during Rapten rapid application does not reliably differ from other NSAIDs. Rapten rapid possesses immunomodulatory effect demonstrated by decreasing the level of serum IgA, activity of 5‘nucleotidase in lymphocytes, neutrophils, monocytes and myeloperoxidase in monocytes.https://rsp.mediar-press.net/rsp/article/view/535rheumatoid arthritisnon-steroid anti-inflammutorv drugspain syndromeimmunomodulatory effect |
| spellingShingle | A. B. Zborovsky B V Zavodovsky L L Derevianko EXPERIENCE WITH RAPTEN RAPID USING IN THE TREATMENT OF ARTICULAR SYNDROME IN RHEUMATOID ARTHRITIS Научно-практическая ревматология rheumatoid arthritis non-steroid anti-inflammutorv drugs pain syndrome immunomodulatory effect |
| title | EXPERIENCE WITH RAPTEN RAPID USING IN THE TREATMENT OF ARTICULAR SYNDROME IN RHEUMATOID ARTHRITIS |
| title_full | EXPERIENCE WITH RAPTEN RAPID USING IN THE TREATMENT OF ARTICULAR SYNDROME IN RHEUMATOID ARTHRITIS |
| title_fullStr | EXPERIENCE WITH RAPTEN RAPID USING IN THE TREATMENT OF ARTICULAR SYNDROME IN RHEUMATOID ARTHRITIS |
| title_full_unstemmed | EXPERIENCE WITH RAPTEN RAPID USING IN THE TREATMENT OF ARTICULAR SYNDROME IN RHEUMATOID ARTHRITIS |
| title_short | EXPERIENCE WITH RAPTEN RAPID USING IN THE TREATMENT OF ARTICULAR SYNDROME IN RHEUMATOID ARTHRITIS |
| title_sort | experience with rapten rapid using in the treatment of articular syndrome in rheumatoid arthritis |
| topic | rheumatoid arthritis non-steroid anti-inflammutorv drugs pain syndrome immunomodulatory effect |
| url | https://rsp.mediar-press.net/rsp/article/view/535 |
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