Variations in the neurobiology of reading in children and adolescents born full term and preterm
Diffusion properties of white matter tracts have been associated with individual differences in reading. Individuals born preterm are at risk of injury to white matter. In this study we compared the associations between diffusion properties of white matter and reading skills in children and adolesce...
| Main Authors: | , , , |
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| Format: | Article |
| Language: | English |
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Elsevier
2016-01-01
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| Series: | NeuroImage: Clinical |
| Subjects: | |
| Online Access: | http://www.sciencedirect.com/science/article/pii/S2213158216300663 |
| _version_ | 1818981345524711424 |
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| author | Katherine E. Travis Michal Ben-Shachar Nathaniel J. Myall Heidi M. Feldman |
| author_facet | Katherine E. Travis Michal Ben-Shachar Nathaniel J. Myall Heidi M. Feldman |
| author_sort | Katherine E. Travis |
| collection | DOAJ |
| description | Diffusion properties of white matter tracts have been associated with individual differences in reading. Individuals born preterm are at risk of injury to white matter. In this study we compared the associations between diffusion properties of white matter and reading skills in children and adolescents born full term and preterm. 45 participants, aged 9–17 years, included 26 preterms (born <36 weeks' gestation) and 19 full-terms. Tract fractional anisotropy (FA) profiles were generated for five bilateral white matter tracts previously associated with reading: anterior superior longitudinal fasciculus (aSLF), arcuate fasciculus (Arc), corticospinal tract (CST), uncinate fasciculus (UF) and inferior longitudinal fasciculus (ILF). Mean scores on reading for the two groups were in the normal range and were not statistically different. In both groups, FA was associated with measures of single word reading and comprehension in the aSLF, AF, CST, and UF. However, correlations were negative in the full term group and positive in the preterm group. These results demonstrate variations in the neurobiology of reading in children born full term and preterm despite comparable reading skills. Findings suggest that efficient information exchange required for strong reading abilities may be accomplished via a different balance of neurobiological mechanisms in different groups of readers. |
| first_indexed | 2024-12-20T17:29:51Z |
| format | Article |
| id | doaj.art-8220365e58324ab1965545aee522e219 |
| institution | Directory Open Access Journal |
| issn | 2213-1582 |
| language | English |
| last_indexed | 2024-12-20T17:29:51Z |
| publishDate | 2016-01-01 |
| publisher | Elsevier |
| record_format | Article |
| series | NeuroImage: Clinical |
| spelling | doaj.art-8220365e58324ab1965545aee522e2192022-12-21T19:31:26ZengElsevierNeuroImage: Clinical2213-15822016-01-0111C55556510.1016/j.nicl.2016.04.003Variations in the neurobiology of reading in children and adolescents born full term and pretermKatherine E. Travis0Michal Ben-Shachar1Nathaniel J. Myall2Heidi M. Feldman3Division of Neonatal and Developmental Medicine, Department of Pediatrics, Stanford University School of Medicine, Palo Alto, CA 94304, United StatesThe Gonda Brain Research Center, Bar Ilan University, Ramat Gan 5290002, IsraelDepartment of Medicine, Stanford University School of Medicine, 300 Pasteur Drive, Stanford, CA 94305, United StatesDivision of Neonatal and Developmental Medicine, Department of Pediatrics, Stanford University School of Medicine, Palo Alto, CA 94304, United StatesDiffusion properties of white matter tracts have been associated with individual differences in reading. Individuals born preterm are at risk of injury to white matter. In this study we compared the associations between diffusion properties of white matter and reading skills in children and adolescents born full term and preterm. 45 participants, aged 9–17 years, included 26 preterms (born <36 weeks' gestation) and 19 full-terms. Tract fractional anisotropy (FA) profiles were generated for five bilateral white matter tracts previously associated with reading: anterior superior longitudinal fasciculus (aSLF), arcuate fasciculus (Arc), corticospinal tract (CST), uncinate fasciculus (UF) and inferior longitudinal fasciculus (ILF). Mean scores on reading for the two groups were in the normal range and were not statistically different. In both groups, FA was associated with measures of single word reading and comprehension in the aSLF, AF, CST, and UF. However, correlations were negative in the full term group and positive in the preterm group. These results demonstrate variations in the neurobiology of reading in children born full term and preterm despite comparable reading skills. Findings suggest that efficient information exchange required for strong reading abilities may be accomplished via a different balance of neurobiological mechanisms in different groups of readers.http://www.sciencedirect.com/science/article/pii/S2213158216300663AnisotropyDiffusion magnetic resonance imaging (dMRI)PrematurityReadingWhite matter |
| spellingShingle | Katherine E. Travis Michal Ben-Shachar Nathaniel J. Myall Heidi M. Feldman Variations in the neurobiology of reading in children and adolescents born full term and preterm NeuroImage: Clinical Anisotropy Diffusion magnetic resonance imaging (dMRI) Prematurity Reading White matter |
| title | Variations in the neurobiology of reading in children and adolescents born full term and preterm |
| title_full | Variations in the neurobiology of reading in children and adolescents born full term and preterm |
| title_fullStr | Variations in the neurobiology of reading in children and adolescents born full term and preterm |
| title_full_unstemmed | Variations in the neurobiology of reading in children and adolescents born full term and preterm |
| title_short | Variations in the neurobiology of reading in children and adolescents born full term and preterm |
| title_sort | variations in the neurobiology of reading in children and adolescents born full term and preterm |
| topic | Anisotropy Diffusion magnetic resonance imaging (dMRI) Prematurity Reading White matter |
| url | http://www.sciencedirect.com/science/article/pii/S2213158216300663 |
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