BioTapestry now provides a web application and improved drawing and layout tools [version 1; referees: 3 approved]

Gene regulatory networks (GRNs) control embryonic development, and to understand this process in depth, researchers need to have a detailed understanding of both the network architecture and its dynamic evolution over time and space. Interactive visualization tools better enable researchers to conce...

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Main Authors: Suzanne M. Paquette, Kalle Leinonen, William J.R. Longabaugh
Format: Article
Language:English
Published: F1000 Research Ltd 2016-01-01
Series:F1000Research
Subjects:
Online Access:http://f1000research.com/articles/5-39/v1
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author Suzanne M. Paquette
Kalle Leinonen
William J.R. Longabaugh
author_facet Suzanne M. Paquette
Kalle Leinonen
William J.R. Longabaugh
author_sort Suzanne M. Paquette
collection DOAJ
description Gene regulatory networks (GRNs) control embryonic development, and to understand this process in depth, researchers need to have a detailed understanding of both the network architecture and its dynamic evolution over time and space. Interactive visualization tools better enable researchers to conceptualize, understand, and share GRN models. BioTapestry is an established application designed to fill this role, and recent enhancements released in Versions 6 and 7 have targeted two major facets of the program. First, we introduced significant improvements for network drawing and automatic layout that have now made it much easier for the user to create larger, more organized network drawings. Second, we revised the program architecture so it could continue to support the current Java desktop Editor program, while introducing a new BioTapestry GRN Viewer that runs as a JavaScript web application in a browser. We have deployed a number of GRN models using this new web application. These improvements will ensure that BioTapestry remains viable as a research tool in the face of the continuing evolution of web technologies, and as our understanding of GRN models grows.
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spelling doaj.art-8220fcdcede7474d88c6ac7111c05e452022-12-21T18:21:52ZengF1000 Research LtdF1000Research2046-14022016-01-01510.12688/f1000research.7620.18206BioTapestry now provides a web application and improved drawing and layout tools [version 1; referees: 3 approved]Suzanne M. Paquette0Kalle Leinonen1William J.R. Longabaugh2Institute for Systems Biology, Seattle, WA, 98109, USAInstitute for Systems Biology, Seattle, WA, 98109, USAInstitute for Systems Biology, Seattle, WA, 98109, USAGene regulatory networks (GRNs) control embryonic development, and to understand this process in depth, researchers need to have a detailed understanding of both the network architecture and its dynamic evolution over time and space. Interactive visualization tools better enable researchers to conceptualize, understand, and share GRN models. BioTapestry is an established application designed to fill this role, and recent enhancements released in Versions 6 and 7 have targeted two major facets of the program. First, we introduced significant improvements for network drawing and automatic layout that have now made it much easier for the user to create larger, more organized network drawings. Second, we revised the program architecture so it could continue to support the current Java desktop Editor program, while introducing a new BioTapestry GRN Viewer that runs as a JavaScript web application in a browser. We have deployed a number of GRN models using this new web application. These improvements will ensure that BioTapestry remains viable as a research tool in the face of the continuing evolution of web technologies, and as our understanding of GRN models grows.http://f1000research.com/articles/5-39/v1BioinformaticsCell Signaling & Trafficking StructuresGenomics
spellingShingle Suzanne M. Paquette
Kalle Leinonen
William J.R. Longabaugh
BioTapestry now provides a web application and improved drawing and layout tools [version 1; referees: 3 approved]
F1000Research
Bioinformatics
Cell Signaling & Trafficking Structures
Genomics
title BioTapestry now provides a web application and improved drawing and layout tools [version 1; referees: 3 approved]
title_full BioTapestry now provides a web application and improved drawing and layout tools [version 1; referees: 3 approved]
title_fullStr BioTapestry now provides a web application and improved drawing and layout tools [version 1; referees: 3 approved]
title_full_unstemmed BioTapestry now provides a web application and improved drawing and layout tools [version 1; referees: 3 approved]
title_short BioTapestry now provides a web application and improved drawing and layout tools [version 1; referees: 3 approved]
title_sort biotapestry now provides a web application and improved drawing and layout tools version 1 referees 3 approved
topic Bioinformatics
Cell Signaling & Trafficking Structures
Genomics
url http://f1000research.com/articles/5-39/v1
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AT williamjrlongabaugh biotapestrynowprovidesawebapplicationandimproveddrawingandlayouttoolsversion1referees3approved