Chaperone-tip adhesin complex is vital for synergistic activation of CFA/I fimbriae biogenesis.

Chaperone-tip adhesin complex is vital for synergistic activation of CFA/I fimbriae biogenesis.

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Colonization factor CFA/I defines the major adhesive fimbriae of enterotoxigenic Escherichia coli and mediates bacterial attachment to host intestinal epithelial cells. The CFA/I fimbria consists of a tip-localized minor adhesive subunit, CfaE, and thousands of copies of the major subunit CfaB polym...

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Bibliographic Details
Main Authors: Li-Hui He, Hao Wang, Yang Liu, Mei Kang, Tao Li, Chang-Cheng Li, Ai-Ping Tong, Yi-Bo Zhu, Ying-Jie Song, Stephen J Savarino, Michael G Prouty, Di Xia, Rui Bao
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2020-10-01
Series:PLoS Pathogens
Online Access:https://doi.org/10.1371/journal.ppat.1008848

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