Cost-effectiveness of a male catch-up human papillomavirus vaccination program in the Netherlands

In the Netherlands, the Health Council has advised that the human papillomavirus (HPV) vaccination should be offered to both boys and girls. Additionally, boys and men up to the age of 26 years should be included in a catch-up program. In this study, we examine the cost-effectiveness of this HPV cat...

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Main Authors: Joost J.M. Simons, Tjalke A. Westra, Maarten J. Postma
Format: Article
Language:English
Published: Elsevier 2022-08-01
Series:Preventive Medicine Reports
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S2211335522001796
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author Joost J.M. Simons
Tjalke A. Westra
Maarten J. Postma
author_facet Joost J.M. Simons
Tjalke A. Westra
Maarten J. Postma
author_sort Joost J.M. Simons
collection DOAJ
description In the Netherlands, the Health Council has advised that the human papillomavirus (HPV) vaccination should be offered to both boys and girls. Additionally, boys and men up to the age of 26 years should be included in a catch-up program. In this study, we examine the cost-effectiveness of this HPV catch-up program.We used a static Markov model to estimate the amount of cancers prevented and the incremental cost-effectiveness ratio (ICER) for different scenarios.Vaccinating men from 12 until the age of 26 years would result in an average of 48 cancer cases prevented in every cohort (an estimated total of 720 cases), with an average ICER of €32,256.We found that the catch-up vaccination program results in a relevant number prevented cases against an acceptable cost-effectiveness ratio. Policymakers should take these findings into account when evaluating a gender-neutral HPV vaccination program in the Netherlands.
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spelling doaj.art-8224b6d888df4b58b7cbe5794e3651122022-12-22T01:53:55ZengElsevierPreventive Medicine Reports2211-33552022-08-0128101872Cost-effectiveness of a male catch-up human papillomavirus vaccination program in the NetherlandsJoost J.M. Simons0Tjalke A. Westra1Maarten J. Postma2Market Access Department, GSK, Van Ash van Wijckstraat 55H, 3811 Amersfoort, the Netherlands; Department of Health Sciences, University of Groningen, University Medical Center, Hanzeplein 1, 9713 GZ Groningen, the Netherlands; Corresponding author at: Market Access Department, GSK, Van Ash van Wijckstraat 55H, 3811 Amersfoort, the Netherlands.Market Access Department, GSK, Van Ash van Wijckstraat 55H, 3811 Amersfoort, the NetherlandsDepartment of Health Sciences, University of Groningen, University Medical Center, Hanzeplein 1, 9713 GZ Groningen, the Netherlands; Unit of Pharmacotherapy, Epidemiology & Economics, University of Groningen, Groningen Research Institute of Pharmacy, A Deusinglaan 1, 9713 AV Groningen, the Netherlands; Department of Economics, Econometrics & Finance, University of Groningen, Faculty of Economics & Business, P.O. Box 800, 9700 AV Groningen, the NetherlandsIn the Netherlands, the Health Council has advised that the human papillomavirus (HPV) vaccination should be offered to both boys and girls. Additionally, boys and men up to the age of 26 years should be included in a catch-up program. In this study, we examine the cost-effectiveness of this HPV catch-up program.We used a static Markov model to estimate the amount of cancers prevented and the incremental cost-effectiveness ratio (ICER) for different scenarios.Vaccinating men from 12 until the age of 26 years would result in an average of 48 cancer cases prevented in every cohort (an estimated total of 720 cases), with an average ICER of €32,256.We found that the catch-up vaccination program results in a relevant number prevented cases against an acceptable cost-effectiveness ratio. Policymakers should take these findings into account when evaluating a gender-neutral HPV vaccination program in the Netherlands.http://www.sciencedirect.com/science/article/pii/S2211335522001796Cost-effectivenessModelingHPVVaccinationCatch-upMale
spellingShingle Joost J.M. Simons
Tjalke A. Westra
Maarten J. Postma
Cost-effectiveness of a male catch-up human papillomavirus vaccination program in the Netherlands
Preventive Medicine Reports
Cost-effectiveness
Modeling
HPV
Vaccination
Catch-up
Male
title Cost-effectiveness of a male catch-up human papillomavirus vaccination program in the Netherlands
title_full Cost-effectiveness of a male catch-up human papillomavirus vaccination program in the Netherlands
title_fullStr Cost-effectiveness of a male catch-up human papillomavirus vaccination program in the Netherlands
title_full_unstemmed Cost-effectiveness of a male catch-up human papillomavirus vaccination program in the Netherlands
title_short Cost-effectiveness of a male catch-up human papillomavirus vaccination program in the Netherlands
title_sort cost effectiveness of a male catch up human papillomavirus vaccination program in the netherlands
topic Cost-effectiveness
Modeling
HPV
Vaccination
Catch-up
Male
url http://www.sciencedirect.com/science/article/pii/S2211335522001796
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