Mucosal-Associated Invariant T (MAIT) Cells Are Impaired in Th17 Associated Primary and Secondary Immunodeficiencies.

Mucosal-Associated Invariant T (MAIT) Cells Are Impaired in Th17 Associated Primary and Secondary Immunodeficiencies.

The recently described Mucosal Associated Invariant T (MAIT) cells mediate specific recognition of bacterial and fungal vitamin B2 metabolites. As innate T cells, they possess broad effector responses, including IFN- including Iproduction, that are comparable to conventional T cell responses. Immuno...

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Bibliographic Details
Main Authors: Yifang Gao, William Rae, Keseva Ananth Ramakrishnan, Gabriela Barcenas-Morales, Rainer Döffinger, Efrem Eren, Saul N Faust, Christian H Ottensmeier, Anthony P Williams
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2016-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4864289?pdf=render

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