Grouping of orally ingested silica nanomaterials via use of an integrated approach to testing and assessment to streamline risk assessment

Grouping of orally ingested silica nanomaterials via use of an integrated approach to testing and assessment to streamline risk assessment

Abstract Background Nanomaterials can exist in different nanoforms (NFs). Their grouping may be supported by the formulation of hypotheses which can be interrogated via integrated approaches to testing and assessment (IATA). IATAs are decision trees that guide the user through tiered testing strateg...

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Bibliographic Details
Main Authors: Luisana Di Cristo, Victor C. Ude, Georgia Tsiliki, Giuseppina Tatulli, Alessio Romaldini, Fiona Murphy, Wendel Wohlleben, Agnes G. Oomen, Pier P. Pompa, Josje Arts, Vicki Stone, Stefania Sabella
Format: Article
Language:English
Published: BMC 2022-12-01
Series:Particle and Fibre Toxicology
Subjects:
Oral dissolution
Nanoforms
Ingestion
Local toxicity
Systemic toxicity
Similarity assessment
Online Access:https://doi.org/10.1186/s12989-022-00508-4

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