The experimental treatment of corneal graft rejection with the interleukin-1 receptor antagonist (IL-1ra) gene.

The experimental treatment of corneal graft rejection with the interleukin-1 receptor antagonist (IL-1ra) gene.

PURPOSE: To investigate the protective effects of interleukin-1 receptor antagonist (IL-1ra) gene transfer in a rat model of corneal graft rejection. METHODS: We constructed a recombinant plasmid (pcDNA3.1-hIL-1ra) with high IL-1ra expression in eukaryotic cells. Using a Wistar-SD rat model of corne...

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Bibliographic Details
Main Authors:	Jin Yuan, Yi Liu, Weilan Huang, Shiyou Zhou, Shiqi Ling, Jiaqi Chen
Format:	Article
Language:	English
Published:	Public Library of Science (PLoS) 2013-01-01
Series:	PLoS ONE
Online Access:	http://europepmc.org/articles/PMC3665808?pdf=render

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