Subepithelial Tumor-like Gastric Cancer

Subepithelial tumor-like gastric cancer (SET-like GC) is a special type of gastric cancer with a relatively low prevalence of approximately 1%. Diagnosing SET-like GC is challenging because the tumor is often covered with normal mucosa. The mechanisms of occurrence of SET-like GC include: 1) excessi...

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Main Authors: Kyoungwon Jung, Moo In Park
Format: Article
Language:English
Published: Yong Chan Lee 2021-06-01
Series:The Korean Journal of Helicobacter and Upper Gastrointestinal Research
Subjects:
Online Access:http://www.helicojournal.org/upload/pdf/kjhugr-2021-0006.pdf
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author Kyoungwon Jung
Moo In Park
author_facet Kyoungwon Jung
Moo In Park
author_sort Kyoungwon Jung
collection DOAJ
description Subepithelial tumor-like gastric cancer (SET-like GC) is a special type of gastric cancer with a relatively low prevalence of approximately 1%. Diagnosing SET-like GC is challenging because the tumor is often covered with normal mucosa. The mechanisms of occurrence of SET-like GC include: 1) excessive infiltration of lymphocytes in the cancer, 2) intensive secretion of mucin by mucinous adenocarcinoma, 3) excessive fibrosis around the cancer, and 4) adenocarcinoma arising from heterotopic gastric glands in the submucosa. It is important to be aware of the endoscopic features of SET-like GC to differentiate it from other subepithelial tumors, to recognize the possibility of SET-like GC, and to make a diagnosis before treatment. In this review, we summarized the epidemiologic and clinicopathologic characteristics of SET-like GC.
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spelling doaj.art-8239b05f6738463dbfc0282ba1ff69cb2022-12-21T18:58:15ZengYong Chan LeeThe Korean Journal of Helicobacter and Upper Gastrointestinal Research1738-33312021-06-0121210611410.7704/kjhugr.2021.0006677Subepithelial Tumor-like Gastric CancerKyoungwon Jung0Moo In Park1Department of Internal Medicine, Kosin University College of Medicine, Busan, KoreaDepartment of Internal Medicine, Kosin University College of Medicine, Busan, KoreaSubepithelial tumor-like gastric cancer (SET-like GC) is a special type of gastric cancer with a relatively low prevalence of approximately 1%. Diagnosing SET-like GC is challenging because the tumor is often covered with normal mucosa. The mechanisms of occurrence of SET-like GC include: 1) excessive infiltration of lymphocytes in the cancer, 2) intensive secretion of mucin by mucinous adenocarcinoma, 3) excessive fibrosis around the cancer, and 4) adenocarcinoma arising from heterotopic gastric glands in the submucosa. It is important to be aware of the endoscopic features of SET-like GC to differentiate it from other subepithelial tumors, to recognize the possibility of SET-like GC, and to make a diagnosis before treatment. In this review, we summarized the epidemiologic and clinicopathologic characteristics of SET-like GC.http://www.helicojournal.org/upload/pdf/kjhugr-2021-0006.pdfgastric cancermucinous adenocarcinomasubepithelial tumor
spellingShingle Kyoungwon Jung
Moo In Park
Subepithelial Tumor-like Gastric Cancer
The Korean Journal of Helicobacter and Upper Gastrointestinal Research
gastric cancer
mucinous adenocarcinoma
subepithelial tumor
title Subepithelial Tumor-like Gastric Cancer
title_full Subepithelial Tumor-like Gastric Cancer
title_fullStr Subepithelial Tumor-like Gastric Cancer
title_full_unstemmed Subepithelial Tumor-like Gastric Cancer
title_short Subepithelial Tumor-like Gastric Cancer
title_sort subepithelial tumor like gastric cancer
topic gastric cancer
mucinous adenocarcinoma
subepithelial tumor
url http://www.helicojournal.org/upload/pdf/kjhugr-2021-0006.pdf
work_keys_str_mv AT kyoungwonjung subepithelialtumorlikegastriccancer
AT mooinpark subepithelialtumorlikegastriccancer