Anticancer and apoptosis-inducing effects of Moringa concanensis using hepG2 cell lines
The objective of the present investigation is focused on the anticancer activity of the ethanolic crude extract of Moringa concanensis leaf and bark against HepG2 cell line. The study was facilitated by collecting the plant sample and subjected to ethanol crude extraction. The anticancer activity of...
| Main Authors: | , , , |
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| Format: | Article |
| Language: | English |
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Bangladesh Pharmacological Society
2014-11-01
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| Series: | Bangladesh Journal of Pharmacology |
| Subjects: | |
| Online Access: | https://www.banglajol.info/index.php/BJP/article/view/20481 |
| _version_ | 1818499188171735040 |
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| author | V. Balamurugan Veluchamy Balakrishnan J. Philip Robinson M. Ramakrishnan |
| author_facet | V. Balamurugan Veluchamy Balakrishnan J. Philip Robinson M. Ramakrishnan |
| author_sort | V. Balamurugan |
| collection | DOAJ |
| description | The objective of the present investigation is focused on the anticancer activity of the ethanolic crude extract of Moringa concanensis leaf and bark against HepG2 cell line. The study was facilitated by collecting the plant sample and subjected to ethanol crude extraction. The anticancer activity of the crude extracted sample against HepG2 cell line was examined by MTT assay. The study confirms that the leaf crude extract of M. concanensis has pronounced anticancer potential against HepG2 cell lines while compared to that of the bark extract. The plant investigated possesses remarkable anticancer activity and hence isolation of the compound contributing to the activity may lead to develop at a novel and natural phytomedicine for the disease. |
| first_indexed | 2024-12-10T20:25:48Z |
| format | Article |
| id | doaj.art-823a36e715a3420aabcbb52aab4868bb |
| institution | Directory Open Access Journal |
| issn | 1991-0088 |
| language | English |
| last_indexed | 2024-12-10T20:25:48Z |
| publishDate | 2014-11-01 |
| publisher | Bangladesh Pharmacological Society |
| record_format | Article |
| series | Bangladesh Journal of Pharmacology |
| spelling | doaj.art-823a36e715a3420aabcbb52aab4868bb2022-12-22T01:34:51ZengBangladesh Pharmacological SocietyBangladesh Journal of Pharmacology1991-00882014-11-0194Anticancer and apoptosis-inducing effects of Moringa concanensis using hepG2 cell linesV. Balamurugan0Veluchamy Balakrishnan1J. Philip Robinson2M. Ramakrishnan3Research and Development Centre, Bharathiar University, Coimbatore 641 046, Tamil NaduResearch and Development Centre, Bharathiar University, Coimbatore 641 046, Tamil NaduDepartment of Biotechnology, K. S. Rangasamy College of Technology (Autonomous), Tiruchengode 637 215, Tamil NaduDepartment of Biotechnology, Sri Vinayaga College of Arts and Science, Ulundurpet 606 107, Tamil NaduThe objective of the present investigation is focused on the anticancer activity of the ethanolic crude extract of Moringa concanensis leaf and bark against HepG2 cell line. The study was facilitated by collecting the plant sample and subjected to ethanol crude extraction. The anticancer activity of the crude extracted sample against HepG2 cell line was examined by MTT assay. The study confirms that the leaf crude extract of M. concanensis has pronounced anticancer potential against HepG2 cell lines while compared to that of the bark extract. The plant investigated possesses remarkable anticancer activity and hence isolation of the compound contributing to the activity may lead to develop at a novel and natural phytomedicine for the disease.https://www.banglajol.info/index.php/BJP/article/view/20481Anti-cancerHepG-2 cell lineMoringa concanensisMTT assay |
| spellingShingle | V. Balamurugan Veluchamy Balakrishnan J. Philip Robinson M. Ramakrishnan Anticancer and apoptosis-inducing effects of Moringa concanensis using hepG2 cell lines Bangladesh Journal of Pharmacology Anti-cancer HepG-2 cell line Moringa concanensis MTT assay |
| title | Anticancer and apoptosis-inducing effects of Moringa concanensis using hepG2 cell lines |
| title_full | Anticancer and apoptosis-inducing effects of Moringa concanensis using hepG2 cell lines |
| title_fullStr | Anticancer and apoptosis-inducing effects of Moringa concanensis using hepG2 cell lines |
| title_full_unstemmed | Anticancer and apoptosis-inducing effects of Moringa concanensis using hepG2 cell lines |
| title_short | Anticancer and apoptosis-inducing effects of Moringa concanensis using hepG2 cell lines |
| title_sort | anticancer and apoptosis inducing effects of moringa concanensis using hepg2 cell lines |
| topic | Anti-cancer HepG-2 cell line Moringa concanensis MTT assay |
| url | https://www.banglajol.info/index.php/BJP/article/view/20481 |
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