The Relationship Between Salivary Alpha Amylase Activity and Score of McGill Pain Questionnaire in Patients With Tension Type Headache
Introduction: Tension-type headache is the most common type of headache across the world. Saliva as a non-invasive medium is used to detect a wide range of diseases. Salivary Alpha-Amylase (SAA) levels has been suggested as a potential indirect marker for detecting Sympathoadrenal Medullary (SAM) ac...
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| Format: | Article |
| Language: | English |
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Iran University of Medical Sciences
2018-01-01
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| Series: | Basic and Clinical Neuroscience |
| Subjects: | |
| Online Access: | http://bcn.iums.ac.ir/browse.php?a_code=A--1079-2&slc_lang=en&sid=1 |
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| author | Mohammad Vahedi Mehrdokht Mazdeh Mehrdad Hajilooi Maryam Farhadian Yasamin Barakian Parastoo Sadr |
| author_facet | Mohammad Vahedi Mehrdokht Mazdeh Mehrdad Hajilooi Maryam Farhadian Yasamin Barakian Parastoo Sadr |
| author_sort | Mohammad Vahedi |
| collection | DOAJ |
| description | Introduction: Tension-type headache is the most common type of headache across the world. Saliva as a non-invasive medium is used to detect a wide range of diseases. Salivary Alpha-Amylase (SAA) levels has been suggested as a potential indirect marker for detecting Sympathoadrenal Medullary (SAM) activity, which is activated by pain. Significant correlation was found between SAA levels and pain scale in patients with chronic pain. The purpose of the present study was to measure SAA activity in Frequent Episodic Tension-Type Headache (FETTH). In addition to the Visual Analogue Scale (VAS), we intend to assess intensity and various aspects of pain by McGill Pain Questionnaire (MPQ).
Methods:.A total of 45 females with FETTH (case group) and 45 healthy voluntary females (control group) were enrolled in our case-control study. Unstimulated saliva by spitting method was taken from each participant.
Results: SAA levels were significantly higher in patients with FETTH (P<0.001) when compared with the control group. There was significant correlation between SAA activity and MPQ score (P<0.001).
Conclusion: This is the first study using MPQ as a subjective means of assessing quality and quantity of pain alongside the VAS as an objective tool for evaluating pain in patients with FETTH. SAA may be an appropriate marker for assessing of pain levels in patients with FETTH. MPQ versus the VAS may be a more accurate measurement tools along VAS. |
| first_indexed | 2024-03-07T17:25:22Z |
| format | Article |
| id | doaj.art-823db7fa5904493996da1283d7980893 |
| institution | Directory Open Access Journal |
| issn | 2008-126X 2228-7442 |
| language | English |
| last_indexed | 2024-03-07T17:25:22Z |
| publishDate | 2018-01-01 |
| publisher | Iran University of Medical Sciences |
| record_format | Article |
| series | Basic and Clinical Neuroscience |
| spelling | doaj.art-823db7fa5904493996da1283d79808932024-03-02T19:16:40ZengIran University of Medical SciencesBasic and Clinical Neuroscience2008-126X2228-74422018-01-01915964The Relationship Between Salivary Alpha Amylase Activity and Score of McGill Pain Questionnaire in Patients With Tension Type HeadacheMohammad Vahedi0Mehrdokht Mazdeh1Mehrdad Hajilooi2Maryam Farhadian3Yasamin Barakian4Parastoo Sadr5 Department of Oral Medicine, School of Dentistry, Hamedan University of Medical Sciences, Hamedan, Iran. Department of Neurology, School of Medicine, Hamedan University of Medical Sciences, Hamedan, Iran. Department of Immunology, School of Medicine, Hamedan University of Medical Sciences, Hamedan, Iran. Research Center for Health Sciences, Hamedan University of Medical Sciences, Hamedan, Iran. Department of Oral Medicine, Faculty of Dentistry, Qom University of Medical Science and Health Services, Qom, Iran. Department of Oral Medicine, Faculty of Dentistry, Mazandaran University of Medical Sciences, Sari, Iran. Introduction: Tension-type headache is the most common type of headache across the world. Saliva as a non-invasive medium is used to detect a wide range of diseases. Salivary Alpha-Amylase (SAA) levels has been suggested as a potential indirect marker for detecting Sympathoadrenal Medullary (SAM) activity, which is activated by pain. Significant correlation was found between SAA levels and pain scale in patients with chronic pain. The purpose of the present study was to measure SAA activity in Frequent Episodic Tension-Type Headache (FETTH). In addition to the Visual Analogue Scale (VAS), we intend to assess intensity and various aspects of pain by McGill Pain Questionnaire (MPQ). Methods:.A total of 45 females with FETTH (case group) and 45 healthy voluntary females (control group) were enrolled in our case-control study. Unstimulated saliva by spitting method was taken from each participant. Results: SAA levels were significantly higher in patients with FETTH (P<0.001) when compared with the control group. There was significant correlation between SAA activity and MPQ score (P<0.001). Conclusion: This is the first study using MPQ as a subjective means of assessing quality and quantity of pain alongside the VAS as an objective tool for evaluating pain in patients with FETTH. SAA may be an appropriate marker for assessing of pain levels in patients with FETTH. MPQ versus the VAS may be a more accurate measurement tools along VAS.http://bcn.iums.ac.ir/browse.php?a_code=A--1079-2&slc_lang=en&sid=1Pain measurement Salivary Alpha Amylase Tension-type headache |
| spellingShingle | Mohammad Vahedi Mehrdokht Mazdeh Mehrdad Hajilooi Maryam Farhadian Yasamin Barakian Parastoo Sadr The Relationship Between Salivary Alpha Amylase Activity and Score of McGill Pain Questionnaire in Patients With Tension Type Headache Basic and Clinical Neuroscience Pain measurement Salivary Alpha Amylase Tension-type headache |
| title | The Relationship Between Salivary Alpha Amylase Activity and Score of McGill Pain Questionnaire in Patients With Tension Type Headache |
| title_full | The Relationship Between Salivary Alpha Amylase Activity and Score of McGill Pain Questionnaire in Patients With Tension Type Headache |
| title_fullStr | The Relationship Between Salivary Alpha Amylase Activity and Score of McGill Pain Questionnaire in Patients With Tension Type Headache |
| title_full_unstemmed | The Relationship Between Salivary Alpha Amylase Activity and Score of McGill Pain Questionnaire in Patients With Tension Type Headache |
| title_short | The Relationship Between Salivary Alpha Amylase Activity and Score of McGill Pain Questionnaire in Patients With Tension Type Headache |
| title_sort | relationship between salivary alpha amylase activity and score of mcgill pain questionnaire in patients with tension type headache |
| topic | Pain measurement Salivary Alpha Amylase Tension-type headache |
| url | http://bcn.iums.ac.ir/browse.php?a_code=A--1079-2&slc_lang=en&sid=1 |
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