Bioenergetic Impairment of Triethylene Glycol Dimethacrylate- (TEGDMA-) Treated Dental Pulp Stem Cells (DPSCs) and Isolated Brain Mitochondria are Amended by Redox Compound Methylene Blue

Bioenergetic Impairment of Triethylene Glycol Dimethacrylate- (TEGDMA-) Treated Dental Pulp Stem Cells (DPSCs) and Isolated Brain Mitochondria are Amended by Redox Compound Methylene Blue

Background: Triethylene glycol dimethacrylate (TEGDMA) monomers released from resin matrix are toxic to dental pulp cells, induce apoptosis, oxidative stress and decrease viability. Recently, mitochondrial complex I (CI) was identified as a potential target of TEGDMA. In isolated mitochondria suppor...

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Bibliographic Details
Main Authors: Krisztina Mikulás, Timea Komlódi, Anna Földes, Gergely Sváb, Gergő Horváth, Ádám Miklós Nagy, Attila Ambrus, Szabolcs Gyulai-Gaál, István Gera, Péter Hermann, Gábor Varga, László Tretter
Format: Article
Language:English
Published: MDPI AG 2020-08-01
Series:Materials
Subjects:
DPSC
methylene blue
mitochondria
oxygen consumption
TEGDMA
Online Access:https://www.mdpi.com/1996-1944/13/16/3472

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