Magnetic Resonance Perfusion-Weighted Imaging in Predicting Hemorrhagic Transformation of Acute Ischemic Stroke: A Retrospective Study
Hemorrhagic transformation (HT) is one of the common complications in patients with acute ischemic stroke (AIS). This study aims to investigate the value of different thresholds of Tmax generated from perfusion-weighted MR imaging (PWI) and the apparent diffusion coefficient (ADC) value in the predi...
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MDPI AG
2023-11-01
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| Series: | Diagnostics |
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| Online Access: | https://www.mdpi.com/2075-4418/13/22/3404 |
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| author | Ming Li Yifan Lv Mingming Wang Yaying Zhang Zilai Pan Yu Luo Haili Zhang Jing Wang |
| author_facet | Ming Li Yifan Lv Mingming Wang Yaying Zhang Zilai Pan Yu Luo Haili Zhang Jing Wang |
| author_sort | Ming Li |
| collection | DOAJ |
| description | Hemorrhagic transformation (HT) is one of the common complications in patients with acute ischemic stroke (AIS). This study aims to investigate the value of different thresholds of Tmax generated from perfusion-weighted MR imaging (PWI) and the apparent diffusion coefficient (ADC) value in the prediction of HT in AIS. A total of 156 AIS patients were enrolled in this study, with 55 patients in the HT group and 101 patients in non-HT group. The clinical baseline data and multi-parametric MRI findings were compared between HT and non-HT groups to identify indicators related to HT. The optimal parameters for predicting HT and the corresponding cutoff values were obtained using the receiver operating characteristic curve analysis of the volumes of ADC < 620 × 10<sup>−6</sup> mm<sup>2</sup>/s and Tmax > 6 s, 8 s, and 10 s. The results showed that the volumes of ADC < 620 × 10<sup>−6</sup> mm<sup>2</sup>/s and Tmax > 6 s, 8 s, and 10 s in the HT group were all significantly larger than that in the non-HT group and were all independent risk factors for HT. Early measurement of the volume of Tmax > 10 s had the highest value, with a cutoff lesion volume of 10.5 mL. |
| first_indexed | 2024-03-09T16:53:54Z |
| format | Article |
| id | doaj.art-823f7c0f1b554a6a95ab5b4fdb83498f |
| institution | Directory Open Access Journal |
| issn | 2075-4418 |
| language | English |
| last_indexed | 2024-03-09T16:53:54Z |
| publishDate | 2023-11-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Diagnostics |
| spelling | doaj.art-823f7c0f1b554a6a95ab5b4fdb83498f2023-11-24T14:37:27ZengMDPI AGDiagnostics2075-44182023-11-011322340410.3390/diagnostics13223404Magnetic Resonance Perfusion-Weighted Imaging in Predicting Hemorrhagic Transformation of Acute Ischemic Stroke: A Retrospective StudyMing Li0Yifan Lv1Mingming Wang2Yaying Zhang3Zilai Pan4Yu Luo5Haili Zhang6Jing Wang7Department of Radiology, Ruijin Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai 200025, ChinaDepartment of Radiology, Shanghai Fourth People’s Hospital, School of Medicine, Tongji University, Shanghai 200434, ChinaDepartment of Radiology, Shanghai Fourth People’s Hospital, School of Medicine, Tongji University, Shanghai 200434, ChinaDepartment of Radiology, Shanghai Fourth People’s Hospital, School of Medicine, Tongji University, Shanghai 200434, ChinaDepartment of Radiology, Ruijin Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai 200025, ChinaDepartment of Radiology, Shanghai Fourth People’s Hospital, School of Medicine, Tongji University, Shanghai 200434, ChinaSoutheast University Hospital, Southeast University, Nanjing 210096, ChinaDepartment of Radiology, Shanghai Fourth People’s Hospital, School of Medicine, Tongji University, Shanghai 200434, ChinaHemorrhagic transformation (HT) is one of the common complications in patients with acute ischemic stroke (AIS). This study aims to investigate the value of different thresholds of Tmax generated from perfusion-weighted MR imaging (PWI) and the apparent diffusion coefficient (ADC) value in the prediction of HT in AIS. A total of 156 AIS patients were enrolled in this study, with 55 patients in the HT group and 101 patients in non-HT group. The clinical baseline data and multi-parametric MRI findings were compared between HT and non-HT groups to identify indicators related to HT. The optimal parameters for predicting HT and the corresponding cutoff values were obtained using the receiver operating characteristic curve analysis of the volumes of ADC < 620 × 10<sup>−6</sup> mm<sup>2</sup>/s and Tmax > 6 s, 8 s, and 10 s. The results showed that the volumes of ADC < 620 × 10<sup>−6</sup> mm<sup>2</sup>/s and Tmax > 6 s, 8 s, and 10 s in the HT group were all significantly larger than that in the non-HT group and were all independent risk factors for HT. Early measurement of the volume of Tmax > 10 s had the highest value, with a cutoff lesion volume of 10.5 mL.https://www.mdpi.com/2075-4418/13/22/3404acute ischemic strokehemorrhagic transformationmagnetic resonance imagingperfusion-weighted imaging |
| spellingShingle | Ming Li Yifan Lv Mingming Wang Yaying Zhang Zilai Pan Yu Luo Haili Zhang Jing Wang Magnetic Resonance Perfusion-Weighted Imaging in Predicting Hemorrhagic Transformation of Acute Ischemic Stroke: A Retrospective Study Diagnostics acute ischemic stroke hemorrhagic transformation magnetic resonance imaging perfusion-weighted imaging |
| title | Magnetic Resonance Perfusion-Weighted Imaging in Predicting Hemorrhagic Transformation of Acute Ischemic Stroke: A Retrospective Study |
| title_full | Magnetic Resonance Perfusion-Weighted Imaging in Predicting Hemorrhagic Transformation of Acute Ischemic Stroke: A Retrospective Study |
| title_fullStr | Magnetic Resonance Perfusion-Weighted Imaging in Predicting Hemorrhagic Transformation of Acute Ischemic Stroke: A Retrospective Study |
| title_full_unstemmed | Magnetic Resonance Perfusion-Weighted Imaging in Predicting Hemorrhagic Transformation of Acute Ischemic Stroke: A Retrospective Study |
| title_short | Magnetic Resonance Perfusion-Weighted Imaging in Predicting Hemorrhagic Transformation of Acute Ischemic Stroke: A Retrospective Study |
| title_sort | magnetic resonance perfusion weighted imaging in predicting hemorrhagic transformation of acute ischemic stroke a retrospective study |
| topic | acute ischemic stroke hemorrhagic transformation magnetic resonance imaging perfusion-weighted imaging |
| url | https://www.mdpi.com/2075-4418/13/22/3404 |
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