Using genomic sequencing for classical genetics in E. coli K12.

Using genomic sequencing for classical genetics in E. coli K12.

We here develop computational methods to facilitate use of 454 whole genome shotgun sequencing to identify mutations in Escherichia coli K12. We had Roche sequence eight related strains derived as spontaneous mutants in a background without a whole genome sequence. They provided difference tables ba...

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Bibliographic Details
Main Authors: Eric Lyons, Michael Freeling, Sydney Kustu, William Inwood
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2011-02-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3045373?pdf=render

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