Seizures in patients with respiratory disease - a retrospective single center study
ABSTRACT Objective: Seizures are a neurological condition commonly experienced during the follow-up period after systemic or metabolic disorders. The aim of the present study was to determine the etiological factors of seizures in patients at a tertiary care chest clinic. Methods: We reviewed al...
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| Format: | Article |
| Language: | English |
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Academia Brasileira de Neurologia (ABNEURO)
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| Series: | Arquivos de Neuro-Psiquiatria |
| Subjects: | |
| Online Access: | http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0004-282X2020000500247&lng=en&tlng=en |
| _version_ | 1828873092892459008 |
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| author | Senay AYDIN Cengiz ÖZDEMIR Ayşegül GÜNDÜZ Meral E. KIZILTAN |
| author_facet | Senay AYDIN Cengiz ÖZDEMIR Ayşegül GÜNDÜZ Meral E. KIZILTAN |
| author_sort | Senay AYDIN |
| collection | DOAJ |
| description | ABSTRACT Objective: Seizures are a neurological condition commonly experienced during the follow-up period after systemic or metabolic disorders. The aim of the present study was to determine the etiological factors of seizures in patients at a tertiary care chest clinic. Methods: We reviewed all neurology consultations that were requested due to seizures in inpatient clinics in a tertiary care hospital specializing in respiratory disorders between January 2011 and January 2018 were retrospectively reviewed. Results: The present study included 705 of 2793 (25.2%) patients who requested consultations for seizures during the study period. The mean age of the sample was 64.05±17.19 years. Of the 705 patients, 307 (43.5%) had a previous history of epilepsy (Group I) and 398 (56.5%) had a first-time seizure and were considered to have symptomatic seizures (Group II). Multiple factors played roles in the development of seizures in 54.8% of the patients. In most patients, metabolic causes, systemic infections, and drug use were identified and an intracranial metastatic mass lesion was the major cause in patients with lung cancer. Rates of hypoxemia and respiratory acidosis were significantly higher in patients with symptomatic seizures (Group II) than in patients with primary epilepsy (Group I). Conclusions: Blood gas changes such as hypoxemia and respiratory acidosis were among the factors statistically associated with the development of symptomatic seizures in patients with respiratory diseases. Additionally, hypoxemia, hypercapnia, and respiratory acidosis were correlated with mortality in patients hospitalized for respiratory system diseases who requested consultations for seizures. |
| first_indexed | 2024-12-13T07:09:09Z |
| format | Article |
| id | doaj.art-8240c95fe36f4a6a88742dd9c7288ffb |
| institution | Directory Open Access Journal |
| issn | 0004-282X 1678-4227 |
| language | English |
| last_indexed | 2024-12-13T07:09:09Z |
| publisher | Academia Brasileira de Neurologia (ABNEURO) |
| record_format | Article |
| series | Arquivos de Neuro-Psiquiatria |
| spelling | doaj.art-8240c95fe36f4a6a88742dd9c7288ffb2022-12-21T23:55:43ZengAcademia Brasileira de Neurologia (ABNEURO)Arquivos de Neuro-Psiquiatria0004-282X1678-422778524725410.1590/0004-282x20190196S0004-282X2020000500247Seizures in patients with respiratory disease - a retrospective single center studySenay AYDINCengiz ÖZDEMIRAyşegül GÜNDÜZMeral E. KIZILTANABSTRACT Objective: Seizures are a neurological condition commonly experienced during the follow-up period after systemic or metabolic disorders. The aim of the present study was to determine the etiological factors of seizures in patients at a tertiary care chest clinic. Methods: We reviewed all neurology consultations that were requested due to seizures in inpatient clinics in a tertiary care hospital specializing in respiratory disorders between January 2011 and January 2018 were retrospectively reviewed. Results: The present study included 705 of 2793 (25.2%) patients who requested consultations for seizures during the study period. The mean age of the sample was 64.05±17.19 years. Of the 705 patients, 307 (43.5%) had a previous history of epilepsy (Group I) and 398 (56.5%) had a first-time seizure and were considered to have symptomatic seizures (Group II). Multiple factors played roles in the development of seizures in 54.8% of the patients. In most patients, metabolic causes, systemic infections, and drug use were identified and an intracranial metastatic mass lesion was the major cause in patients with lung cancer. Rates of hypoxemia and respiratory acidosis were significantly higher in patients with symptomatic seizures (Group II) than in patients with primary epilepsy (Group I). Conclusions: Blood gas changes such as hypoxemia and respiratory acidosis were among the factors statistically associated with the development of symptomatic seizures in patients with respiratory diseases. Additionally, hypoxemia, hypercapnia, and respiratory acidosis were correlated with mortality in patients hospitalized for respiratory system diseases who requested consultations for seizures.http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0004-282X2020000500247&lng=en&tlng=enconvulsõesdoenças respiratóriashipóxiahipercapniaacidose respiratória |
| spellingShingle | Senay AYDIN Cengiz ÖZDEMIR Ayşegül GÜNDÜZ Meral E. KIZILTAN Seizures in patients with respiratory disease - a retrospective single center study Arquivos de Neuro-Psiquiatria convulsões doenças respiratórias hipóxia hipercapnia acidose respiratória |
| title | Seizures in patients with respiratory disease - a retrospective single center study |
| title_full | Seizures in patients with respiratory disease - a retrospective single center study |
| title_fullStr | Seizures in patients with respiratory disease - a retrospective single center study |
| title_full_unstemmed | Seizures in patients with respiratory disease - a retrospective single center study |
| title_short | Seizures in patients with respiratory disease - a retrospective single center study |
| title_sort | seizures in patients with respiratory disease a retrospective single center study |
| topic | convulsões doenças respiratórias hipóxia hipercapnia acidose respiratória |
| url | http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0004-282X2020000500247&lng=en&tlng=en |
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