A single point mutation expands the applicability of ostreolysin A6 in biomedicine

A single point mutation expands the applicability of ostreolysin A6 in biomedicine

Abstract An aegerolysin protein ostreolysin A6 (OlyA6) binds to cholesterol-complexed sphingomyelin and can be used for specific labelling of lipid rafts. In addition, OlyA6 interacts with even higher affinity with ceramide phosphoethanolamine (CPE), a sphingolipid that dominates in invertebrate cel...

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Bibliographic Details
Main Authors: Anastasija Panevska, Nastja Čegovnik, Klavdija Fortuna, Alen Vukovič, Maja Grundner, Špela Modic, Gregor Bajc, Matej Skočaj, Martina Mravinec Bohte, Lara Larisa Popošek, Primož Žigon, Jaka Razinger, Peter Veranič, Nataša Resnik, Kristina Sepčić
Format: Article
Language:English
Published: Nature Portfolio 2023-02-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-023-28949-7

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