The Application of ATR-FTIR Spectroscopy and the Reversible DNA Conformation as a Sensor to Test the Effectiveness of Platinum(II) Anticancer Drugs

The Application of ATR-FTIR Spectroscopy and the Reversible DNA Conformation as a Sensor to Test the Effectiveness of Platinum(II) Anticancer Drugs

Platinum(II) complexes have been found to be effective against cancer cells. Cisplatin curbs cell replication by interacting with the deoxyribonucleic acid (DNA), reducing cell proliferation and eventually leading to cell death. In order to investigate the ability of platinum complexes to affect can...

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Bibliographic Details
Main Authors: Khansa Al-Jorani, Anja Rüther, Miguela Martin, Rukshani Haputhanthri, Glen B. Deacon, Hsiu Lin Li, Bayden R. Wood
Format: Article
Language:English
Published: MDPI AG 2018-12-01
Series:Sensors
Subjects:
platinum
DNA
IR
Online Access:https://www.mdpi.com/1424-8220/18/12/4297

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