Molecular signature of cancer stem cells isolated from prostate carcinoma and expression of stem markers in different Gleason grades and metastasis

Molecular signature of cancer stem cells isolated from prostate carcinoma and expression of stem markers in different Gleason grades and metastasis

Prostate cancer (PCa) is the most frequently diagnosed malignancy in men worldwide. Chemotherapy response is very poor and resistance to hormone-based treatments is frequent in advances stages. Recently, tumor-initiating cells or cancer stem cells (CSCs) have been identified in several cancers, incl...

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Bibliographic Details
Main Authors: Enrique A Castellón, Rodrigo Valenzuela, Jorge Lillo, Viviana Castillo, Héctor R Contreras, Iván Gallegos, Alejandro Mercado, Christian Huidobro
Format: Article
Language:English
Published: BMC 2012-01-01
Series:Biological Research
Subjects:
prostate cancer
cancer stem cell
spheres cultures
Online Access:http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0716-97602012000300011

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