Stability of MRI Radiomics Features of Hippocampus: An Integrated Analysis of Test-Retest and Inter-Observer Variability
Radiomics is a quantitative method to extract medical features that can extend to details that are invisible to human eyes. Studies have suggested that radiomics of the hippocampus is a potential imaging biomarker for several diseases, including Alzheimer's disease, mild cognitive impairment, a...
| Main Authors: | , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
IEEE
2019-01-01
|
| Series: | IEEE Access |
| Subjects: | |
| Online Access: | https://ieeexplore.ieee.org/document/8753651/ |
| _version_ | 1818380670918983680 |
|---|---|
| author | Zhuoran Li Huichuan Duan Kun Zhao Yanhui Ding |
| author_facet | Zhuoran Li Huichuan Duan Kun Zhao Yanhui Ding |
| author_sort | Zhuoran Li |
| collection | DOAJ |
| description | Radiomics is a quantitative method to extract medical features that can extend to details that are invisible to human eyes. Studies have suggested that radiomics of the hippocampus is a potential imaging biomarker for several diseases, including Alzheimer's disease, mild cognitive impairment, and multiple sclerosis. This study investigates the test-retest reproducibility of radiomics features of the hippocampus. For this purpose, the intra-class correlation coefficient (ICC) and overall concordance correlation coefficient (OCCC) of the radiomics features of the hippocampus were well studied in four datasets consisting of 15, 19, 23, and 3 subjects who were scanned three, two, four, and forty times, respectively. The results highlight that the hippocampal texture features are the most repeatable, and that texture features are a possible neuroimaging biomarker for clinical studies. |
| first_indexed | 2024-12-14T02:22:23Z |
| format | Article |
| id | doaj.art-82464a4864264909b433daf2d93f9458 |
| institution | Directory Open Access Journal |
| issn | 2169-3536 |
| language | English |
| last_indexed | 2024-12-14T02:22:23Z |
| publishDate | 2019-01-01 |
| publisher | IEEE |
| record_format | Article |
| series | IEEE Access |
| spelling | doaj.art-82464a4864264909b433daf2d93f94582022-12-21T23:20:27ZengIEEEIEEE Access2169-35362019-01-017971069711610.1109/ACCESS.2019.29237558753651Stability of MRI Radiomics Features of Hippocampus: An Integrated Analysis of Test-Retest and Inter-Observer VariabilityZhuoran Li0https://orcid.org/0000-0002-5623-8590Huichuan Duan1Kun Zhao2Yanhui Ding3School of Information Science and Engineering, Shandong Normal University, Jinan, ChinaSchool of Information Science and Engineering, Shandong Normal University, Jinan, ChinaSchool of Information Science and Engineering, Shandong Normal University, Jinan, ChinaSchool of Information Science and Engineering, Shandong Normal University, Jinan, ChinaRadiomics is a quantitative method to extract medical features that can extend to details that are invisible to human eyes. Studies have suggested that radiomics of the hippocampus is a potential imaging biomarker for several diseases, including Alzheimer's disease, mild cognitive impairment, and multiple sclerosis. This study investigates the test-retest reproducibility of radiomics features of the hippocampus. For this purpose, the intra-class correlation coefficient (ICC) and overall concordance correlation coefficient (OCCC) of the radiomics features of the hippocampus were well studied in four datasets consisting of 15, 19, 23, and 3 subjects who were scanned three, two, four, and forty times, respectively. The results highlight that the hippocampal texture features are the most repeatable, and that texture features are a possible neuroimaging biomarker for clinical studies.https://ieeexplore.ieee.org/document/8753651/Hippocampusradiomics featuresrepeatability |
| spellingShingle | Zhuoran Li Huichuan Duan Kun Zhao Yanhui Ding Stability of MRI Radiomics Features of Hippocampus: An Integrated Analysis of Test-Retest and Inter-Observer Variability IEEE Access Hippocampus radiomics features repeatability |
| title | Stability of MRI Radiomics Features of Hippocampus: An Integrated Analysis of Test-Retest and Inter-Observer Variability |
| title_full | Stability of MRI Radiomics Features of Hippocampus: An Integrated Analysis of Test-Retest and Inter-Observer Variability |
| title_fullStr | Stability of MRI Radiomics Features of Hippocampus: An Integrated Analysis of Test-Retest and Inter-Observer Variability |
| title_full_unstemmed | Stability of MRI Radiomics Features of Hippocampus: An Integrated Analysis of Test-Retest and Inter-Observer Variability |
| title_short | Stability of MRI Radiomics Features of Hippocampus: An Integrated Analysis of Test-Retest and Inter-Observer Variability |
| title_sort | stability of mri radiomics features of hippocampus an integrated analysis of test retest and inter observer variability |
| topic | Hippocampus radiomics features repeatability |
| url | https://ieeexplore.ieee.org/document/8753651/ |
| work_keys_str_mv | AT zhuoranli stabilityofmriradiomicsfeaturesofhippocampusanintegratedanalysisoftestretestandinterobservervariability AT huichuanduan stabilityofmriradiomicsfeaturesofhippocampusanintegratedanalysisoftestretestandinterobservervariability AT kunzhao stabilityofmriradiomicsfeaturesofhippocampusanintegratedanalysisoftestretestandinterobservervariability AT yanhuiding stabilityofmriradiomicsfeaturesofhippocampusanintegratedanalysisoftestretestandinterobservervariability |