TIMP-1 is upregulated, but not essential in hepatic fibrogenesis and carcinogenesis in mice
Abstract Tissue inhibitor of metalloproteinases-1 (TIMP-1) is upregulated during hepatic fibrogenesis and considered to promote fibrosis in the injured liver by inhibition of matrix metalloproteases (MMP) and degradation of extracellular matrix. Moreover, TIMP-1 displays anti-apoptotic properties, i...
| Những tác giả chính: | , , , , , , |
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| Định dạng: | Bài viết |
| Ngôn ngữ: | English |
| Được phát hành: |
Nature Portfolio
2017-04-01
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| Loạt: | Scientific Reports |
| Truy cập trực tuyến: | https://doi.org/10.1038/s41598-017-00671-1 |