Monitoring the Subolesin Vaccine Field Trial for Safer Control of Cattle Ticks Amidst Increasing Acaricide Resistance in Uganda
A collaboration program was established between the group of Health and Biotechnology (SaBio) of the IREC Institute of Game and Wildlife Research (CSIC-UCLM-JCCM, Spain) and the National Agricultural Research Organization of Uganda (NARO) for the development of vaccines for the control of cattle tic...
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| Format: | Article |
| Language: | English |
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MDPI AG
2022-09-01
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| Series: | Vaccines |
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| Online Access: | https://www.mdpi.com/2076-393X/10/10/1594 |
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| author | Fredrick Kabi Moses Dhikusooka Moses Matovu Swidiq Mugerwa Paul Kasaija Patrick Emudong Halid Kirunda Marinela Contreras Christian Gortazar Jose De la Fuente |
| author_facet | Fredrick Kabi Moses Dhikusooka Moses Matovu Swidiq Mugerwa Paul Kasaija Patrick Emudong Halid Kirunda Marinela Contreras Christian Gortazar Jose De la Fuente |
| author_sort | Fredrick Kabi |
| collection | DOAJ |
| description | A collaboration program was established between the group of Health and Biotechnology (SaBio) of the IREC Institute of Game and Wildlife Research (CSIC-UCLM-JCCM, Spain) and the National Agricultural Research Organization of Uganda (NARO) for the development of vaccines for the control of cattle ticks in Uganda. Controlled pen trials identified a tick protective antigen, <i>Rhipicephalus appendiculatus</i> Subolesin, and a cross-species-effective vaccine formulation. As the next step, a controlled vaccine field trial has been approved by Ugandan state regulatory authorities, the Uganda National Council for Science and Technology (UNCST) and the National Drug Authority (NDA), to evaluate the efficacy and effectiveness of the vaccine formulation for the control of cattle tick infestations under field conditions. The results of this trial may lead to the approval of the vaccine for application in Uganda to improve cattle health and production while reducing the use of acaricides. |
| first_indexed | 2024-03-09T19:25:00Z |
| format | Article |
| id | doaj.art-824d2120a2234927acc3af57f900279a |
| institution | Directory Open Access Journal |
| issn | 2076-393X |
| language | English |
| last_indexed | 2024-03-09T19:25:00Z |
| publishDate | 2022-09-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Vaccines |
| spelling | doaj.art-824d2120a2234927acc3af57f900279a2023-11-24T03:02:38ZengMDPI AGVaccines2076-393X2022-09-011010159410.3390/vaccines10101594Monitoring the Subolesin Vaccine Field Trial for Safer Control of Cattle Ticks Amidst Increasing Acaricide Resistance in UgandaFredrick Kabi0Moses Dhikusooka1Moses Matovu2Swidiq Mugerwa3Paul Kasaija4Patrick Emudong5Halid Kirunda6Marinela Contreras7Christian Gortazar8Jose De la Fuente9National Livestock Resources Research Institute (NaLIRRI/NARO), Kampala P.O. Box 5704, UgandaNational Livestock Resources Research Institute (NaLIRRI/NARO), Kampala P.O. Box 5704, UgandaNational Livestock Resources Research Institute (NaLIRRI/NARO), Kampala P.O. Box 5704, UgandaNational Livestock Resources Research Institute (NaLIRRI/NARO), Kampala P.O. Box 5704, UgandaNational Livestock Resources Research Institute (NaLIRRI/NARO), Kampala P.O. Box 5704, UgandaNational Livestock Resources Research Institute (NaLIRRI/NARO), Kampala P.O. Box 5704, UgandaMbarara Zonal Agricultural Research and Development Institute (MbaZARDI), Mbarara City P.O. Box 389, UgandaSaBio, Instituto de Investigación en Recursos Cinegéticos (IREC), Consejo Superior de Investigaciones Cientí ficas (CSIC), Universidad de Castilla-La Mancha (UCLM)-Junta de Comunidades de Castilla-La Mancha (JCCM), Ronda de Toledo 12, 13005 Ciudad Real, SpainSaBio, Instituto de Investigación en Recursos Cinegéticos (IREC), Consejo Superior de Investigaciones Cientí ficas (CSIC), Universidad de Castilla-La Mancha (UCLM)-Junta de Comunidades de Castilla-La Mancha (JCCM), Ronda de Toledo 12, 13005 Ciudad Real, SpainSaBio, Instituto de Investigación en Recursos Cinegéticos (IREC), Consejo Superior de Investigaciones Cientí ficas (CSIC), Universidad de Castilla-La Mancha (UCLM)-Junta de Comunidades de Castilla-La Mancha (JCCM), Ronda de Toledo 12, 13005 Ciudad Real, SpainA collaboration program was established between the group of Health and Biotechnology (SaBio) of the IREC Institute of Game and Wildlife Research (CSIC-UCLM-JCCM, Spain) and the National Agricultural Research Organization of Uganda (NARO) for the development of vaccines for the control of cattle ticks in Uganda. Controlled pen trials identified a tick protective antigen, <i>Rhipicephalus appendiculatus</i> Subolesin, and a cross-species-effective vaccine formulation. As the next step, a controlled vaccine field trial has been approved by Ugandan state regulatory authorities, the Uganda National Council for Science and Technology (UNCST) and the National Drug Authority (NDA), to evaluate the efficacy and effectiveness of the vaccine formulation for the control of cattle tick infestations under field conditions. The results of this trial may lead to the approval of the vaccine for application in Uganda to improve cattle health and production while reducing the use of acaricides.https://www.mdpi.com/2076-393X/10/10/1594Subolesinvaccinecattletickfield trial |
| spellingShingle | Fredrick Kabi Moses Dhikusooka Moses Matovu Swidiq Mugerwa Paul Kasaija Patrick Emudong Halid Kirunda Marinela Contreras Christian Gortazar Jose De la Fuente Monitoring the Subolesin Vaccine Field Trial for Safer Control of Cattle Ticks Amidst Increasing Acaricide Resistance in Uganda Vaccines Subolesin vaccine cattle tick field trial |
| title | Monitoring the Subolesin Vaccine Field Trial for Safer Control of Cattle Ticks Amidst Increasing Acaricide Resistance in Uganda |
| title_full | Monitoring the Subolesin Vaccine Field Trial for Safer Control of Cattle Ticks Amidst Increasing Acaricide Resistance in Uganda |
| title_fullStr | Monitoring the Subolesin Vaccine Field Trial for Safer Control of Cattle Ticks Amidst Increasing Acaricide Resistance in Uganda |
| title_full_unstemmed | Monitoring the Subolesin Vaccine Field Trial for Safer Control of Cattle Ticks Amidst Increasing Acaricide Resistance in Uganda |
| title_short | Monitoring the Subolesin Vaccine Field Trial for Safer Control of Cattle Ticks Amidst Increasing Acaricide Resistance in Uganda |
| title_sort | monitoring the subolesin vaccine field trial for safer control of cattle ticks amidst increasing acaricide resistance in uganda |
| topic | Subolesin vaccine cattle tick field trial |
| url | https://www.mdpi.com/2076-393X/10/10/1594 |
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