Abrogation of junctional adhesion molecule-A expression induces cell apoptosis and reduces breast cancer progression.

Abrogation of junctional adhesion molecule-A expression induces cell apoptosis and reduces breast cancer progression.

Intercellular junctions promote homotypic cell to cell adhesion and transfer intracellular signals which control cell growth and apoptosis. Junctional adhesion molecule-A (JAM-A) is a transmembrane immunoglobulin located at tight junctions of normal epithelial cells of mammary ducts and glands. In t...

Full description

Bibliographic Details
Main Authors: Masato Murakami, Costanza Giampietro, Monica Giannotta, Monica Corada, Ilaria Torselli, Fabrizio Orsenigo, Andrea Cocito, Giovanni d'Ario, Giovanni Mazzarol, Stefano Confalonieri, Pier Paolo Di Fiore, Elisabetta Dejana
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2011-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3117883?pdf=render

Internet

http://europepmc.org/articles/PMC3117883?pdf=render

Similar Items