SOX2OT Long Noncoding RNA Is Regulated by the UPR in Oestrogen Receptor-Positive Breast Cancer

SOX2OT Long Noncoding RNA Is Regulated by the UPR in Oestrogen Receptor-Positive Breast Cancer

Endoplasmic reticulum (ENR) stress perturbs cell homeostasis and induces the unfolded protein response (UPR). In breast cancer, this process is activated by oestrogen deprivation and is associated with tamoxifen resistance. We present evidence that the transcription factor SOX2 and the long noncodin...

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Bibliographic Details
Main Authors: Carole Ferraro-Peyret, Marjan E. Askarian-Amiri, Debina Sarkar, Wayne R. Joseph, Herah Hansji, Bruce C. Baguley, Euphemia Y. Leung
Format: Article
Language:English
Published: MDPI AG 2021-05-01
Series:Sci
Subjects:
breast cancer
LncRNA
SOX2OT
SOX2
UPR
4-OH tamoxifen
Online Access:https://www.mdpi.com/2413-4155/3/2/26

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