Brachytherapy of stage II mobile tongue carcinoma. Prediction of local control and QOL
<p>Abstract</p> <p>Background</p> <p>There is no consensus as to the prognostic model for brachytherapy of tongue carcinoma. This study was designed to evaluate the prognostic factors for local control based on a large population under a unified treatment policy.</p&...
| Main Authors: | , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
BMC
2006-07-01
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| Series: | Radiation Oncology |
| Online Access: | http://www.ro-journal.com/content/1/1/21 |
| _version_ | 1818270102175350784 |
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| author | Watanabe Hiroshi Yoshimura Ryo-ichi Shibuya Hitoshi Oota Sayako Miura Masahiko |
| author_facet | Watanabe Hiroshi Yoshimura Ryo-ichi Shibuya Hitoshi Oota Sayako Miura Masahiko |
| author_sort | Watanabe Hiroshi |
| collection | DOAJ |
| description | <p>Abstract</p> <p>Background</p> <p>There is no consensus as to the prognostic model for brachytherapy of tongue carcinoma. This study was designed to evaluate the prognostic factors for local control based on a large population under a unified treatment policy.</p> <p>Results</p> <p>Between 1970 and 1998, 433 patients with stage II tongue squamous cell carcinoma were treated by low-dose-rate brachytherapy. This series included 277 patients treated with a linear source with a minimum follow-up of 3 years. A spacer was introduced in 1987. The primary local control rates were 85.6%.</p> <p>Conclusion</p> <p>In the multivariate analysis, an invasive growth pattern was a significant factor for local recurrence. The disease-related survival was influenced by old age and an invasive growth pattern. A spacer lowered mandibular bone complications. The growth pattern was the most important factor for recurrence. Brachytherapy was associated with a high cure rate and the use of spacers brought about good quality of life (QOL).</p> |
| first_indexed | 2024-12-12T21:04:56Z |
| format | Article |
| id | doaj.art-82592f0a3bb04bb585b2d2851a1b067b |
| institution | Directory Open Access Journal |
| issn | 1748-717X |
| language | English |
| last_indexed | 2024-12-12T21:04:56Z |
| publishDate | 2006-07-01 |
| publisher | BMC |
| record_format | Article |
| series | Radiation Oncology |
| spelling | doaj.art-82592f0a3bb04bb585b2d2851a1b067b2022-12-22T00:12:02ZengBMCRadiation Oncology1748-717X2006-07-01112110.1186/1748-717X-1-21Brachytherapy of stage II mobile tongue carcinoma. Prediction of local control and QOLWatanabe HiroshiYoshimura Ryo-ichiShibuya HitoshiOota SayakoMiura Masahiko<p>Abstract</p> <p>Background</p> <p>There is no consensus as to the prognostic model for brachytherapy of tongue carcinoma. This study was designed to evaluate the prognostic factors for local control based on a large population under a unified treatment policy.</p> <p>Results</p> <p>Between 1970 and 1998, 433 patients with stage II tongue squamous cell carcinoma were treated by low-dose-rate brachytherapy. This series included 277 patients treated with a linear source with a minimum follow-up of 3 years. A spacer was introduced in 1987. The primary local control rates were 85.6%.</p> <p>Conclusion</p> <p>In the multivariate analysis, an invasive growth pattern was a significant factor for local recurrence. The disease-related survival was influenced by old age and an invasive growth pattern. A spacer lowered mandibular bone complications. The growth pattern was the most important factor for recurrence. Brachytherapy was associated with a high cure rate and the use of spacers brought about good quality of life (QOL).</p>http://www.ro-journal.com/content/1/1/21 |
| spellingShingle | Watanabe Hiroshi Yoshimura Ryo-ichi Shibuya Hitoshi Oota Sayako Miura Masahiko Brachytherapy of stage II mobile tongue carcinoma. Prediction of local control and QOL Radiation Oncology |
| title | Brachytherapy of stage II mobile tongue carcinoma. Prediction of local control and QOL |
| title_full | Brachytherapy of stage II mobile tongue carcinoma. Prediction of local control and QOL |
| title_fullStr | Brachytherapy of stage II mobile tongue carcinoma. Prediction of local control and QOL |
| title_full_unstemmed | Brachytherapy of stage II mobile tongue carcinoma. Prediction of local control and QOL |
| title_short | Brachytherapy of stage II mobile tongue carcinoma. Prediction of local control and QOL |
| title_sort | brachytherapy of stage ii mobile tongue carcinoma prediction of local control and qol |
| url | http://www.ro-journal.com/content/1/1/21 |
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