| Summary: | The pulp–tooth area ratio (PTR) from radiographic dental archives is considered useful for age estimation in the forensic field. Since there have been no studies conducted in the Saudi Arabian population using the PTR method, this study aimed to assess the relationship between the pulp–tooth area ratio of maxillary canines and central incisors and chronological age among Saudi Arabian adults using CBCT and to compare the selected teeth’s predictive power. For this, 100 CBCT scans of 62 male and 38 female patients aged between 20 and 60 years were assessed using OnDemand 3D DentalTM software (Cybermed Co., Tustin, CA, USA) in the axial and sagittal section of each tooth. The mean age estimated using the PTR of the maxillary incisors (39.98 years) was higher than the canines’ (37.9 years). A negative correlation coefficient ‘r’ value was seen between PTR and age. The strongest inverse correlation was noted between age and incisor axial view (0.47) (<i>p</i> < 0.05), Maxillary central incisors had higher R<sup>2</sup> in both genders (males: PTRS-0.18, PTRA-0.17; females: PTRS-0.19, PTRA-0.35) than canines. We conclude a weak correlation between the pulp–tooth ratio and chronological age estimation. CBCT pulp–tooth ratios of axial and sagittal sections of incisors were inconclusive in estimating the age of Saudi Arabian individuals owing to their low coefficient of estimation. Among the tooth types studied, maxillary incisors were better predictors than canines.
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