Comorbidities and in-hospital death of viral pneumonia adults admitted to SUS (2002–2015)
ABSTRACT OBJECTIVE To identify demographic and clinical characteristics of adult patients hospitalized in the Brazilian Unified Health System (SUS) due to viral pneumonia and investigate the association between some comorbidities and death during hospitalization. METHODS This retrospective cohor...
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| Format: | Article |
| Language: | English |
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Universidade de São Paulo
2021-07-01
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| Series: | Revista de Saúde Pública |
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| Online Access: | http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0034-89102021000100236&tlng=en |
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| author | Thais Piazza Daniela Pena Moreira Hugo André da Rocha Agner Pereira Lana Ilka Afonso Reis Marcos Antônio da Cunha Santos Augusto Afonso Guerra-Júnior Mariangela Leal Cherchiglia |
| author_facet | Thais Piazza Daniela Pena Moreira Hugo André da Rocha Agner Pereira Lana Ilka Afonso Reis Marcos Antônio da Cunha Santos Augusto Afonso Guerra-Júnior Mariangela Leal Cherchiglia |
| author_sort | Thais Piazza |
| collection | DOAJ |
| description | ABSTRACT OBJECTIVE To identify demographic and clinical characteristics of adult patients hospitalized in the Brazilian Unified Health System (SUS) due to viral pneumonia and investigate the association between some comorbidities and death during hospitalization. METHODS This retrospective cohort study was conducted with secondary data of adults admitted to SUS due to viral pneumonia between 2002 and 2015. Patient profile was characterized based on demographic and clinical variables. The association between the ten Elixhauser comorbidities and in-hospital death was investigated using Poisson regression models with robust standard errors. Results were quantified as incidence rate ratio (IRR) with 95% confidence intervals (CI), and we built five models using successive inclusion of variables blocks. RESULTS Hospital admissions for viral pneumonias decreased throughout the study period, and it was observed that 5.8% of hospitalized patients had an in-hospital death. We observed significant differences in demographic and clinical characteristics by comparing individuals who died during hospitalization with those who did not, with the occurrence of one or more comorbidities being more expressive among patients who died. Although not considered risk factors for in-hospital death, chronic pulmonary disease and congestive heart failure were the most common comorbidities. Conversely, IRR for in-hospital death increased with other neurological disorders, diabetes, cancer, obesity, and especially with HIV/AIDS. CONCLUSIONS Individuals presenting with pulmonary and cardiovascular diseases require proper attention during hospitalization, as well as those with other neurological diseases, diabetes, cancer, obesity, and especially HIV/AIDS. Understanding the influence of chronic diseases on viral infections may support the healthcare system in achieving better outcomes. |
| first_indexed | 2024-12-20T09:40:31Z |
| format | Article |
| id | doaj.art-8261589369d444f89aba9236436a66d4 |
| institution | Directory Open Access Journal |
| issn | 1518-8787 |
| language | English |
| last_indexed | 2024-12-20T09:40:31Z |
| publishDate | 2021-07-01 |
| publisher | Universidade de São Paulo |
| record_format | Article |
| series | Revista de Saúde Pública |
| spelling | doaj.art-8261589369d444f89aba9236436a66d42022-12-21T19:44:54ZengUniversidade de São PauloRevista de Saúde Pública1518-87872021-07-015510.11606/s1518-8787.2021055003109Comorbidities and in-hospital death of viral pneumonia adults admitted to SUS (2002–2015)Thais Piazzahttps://orcid.org/0000-0001-9385-7609Daniela Pena Moreirahttps://orcid.org/0000-0002-3109-1342Hugo André da Rochahttps://orcid.org/0000-0001-6433-0568Agner Pereira Lanahttps://orcid.org/0000-0001-7654-1063Ilka Afonso Reishttps://orcid.org/0000-0001-7199-8590Marcos Antônio da Cunha Santoshttps://orcid.org/0000-0002-5228-8822Augusto Afonso Guerra-Júniorhttps://orcid.org/0000-0001-5256-0577Mariangela Leal Cherchigliahttps://orcid.org/0000-0001-5622-567XABSTRACT OBJECTIVE To identify demographic and clinical characteristics of adult patients hospitalized in the Brazilian Unified Health System (SUS) due to viral pneumonia and investigate the association between some comorbidities and death during hospitalization. METHODS This retrospective cohort study was conducted with secondary data of adults admitted to SUS due to viral pneumonia between 2002 and 2015. Patient profile was characterized based on demographic and clinical variables. The association between the ten Elixhauser comorbidities and in-hospital death was investigated using Poisson regression models with robust standard errors. Results were quantified as incidence rate ratio (IRR) with 95% confidence intervals (CI), and we built five models using successive inclusion of variables blocks. RESULTS Hospital admissions for viral pneumonias decreased throughout the study period, and it was observed that 5.8% of hospitalized patients had an in-hospital death. We observed significant differences in demographic and clinical characteristics by comparing individuals who died during hospitalization with those who did not, with the occurrence of one or more comorbidities being more expressive among patients who died. Although not considered risk factors for in-hospital death, chronic pulmonary disease and congestive heart failure were the most common comorbidities. Conversely, IRR for in-hospital death increased with other neurological disorders, diabetes, cancer, obesity, and especially with HIV/AIDS. CONCLUSIONS Individuals presenting with pulmonary and cardiovascular diseases require proper attention during hospitalization, as well as those with other neurological diseases, diabetes, cancer, obesity, and especially HIV/AIDS. Understanding the influence of chronic diseases on viral infections may support the healthcare system in achieving better outcomes.http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0034-89102021000100236&tlng=enPneumonia, Viral, epidemiologyRisk FactorsComorbidityHospitalizationHospital Mortality |
| spellingShingle | Thais Piazza Daniela Pena Moreira Hugo André da Rocha Agner Pereira Lana Ilka Afonso Reis Marcos Antônio da Cunha Santos Augusto Afonso Guerra-Júnior Mariangela Leal Cherchiglia Comorbidities and in-hospital death of viral pneumonia adults admitted to SUS (2002–2015) Revista de Saúde Pública Pneumonia, Viral, epidemiology Risk Factors Comorbidity Hospitalization Hospital Mortality |
| title | Comorbidities and in-hospital death of viral pneumonia adults admitted to SUS (2002–2015) |
| title_full | Comorbidities and in-hospital death of viral pneumonia adults admitted to SUS (2002–2015) |
| title_fullStr | Comorbidities and in-hospital death of viral pneumonia adults admitted to SUS (2002–2015) |
| title_full_unstemmed | Comorbidities and in-hospital death of viral pneumonia adults admitted to SUS (2002–2015) |
| title_short | Comorbidities and in-hospital death of viral pneumonia adults admitted to SUS (2002–2015) |
| title_sort | comorbidities and in hospital death of viral pneumonia adults admitted to sus 2002 2015 |
| topic | Pneumonia, Viral, epidemiology Risk Factors Comorbidity Hospitalization Hospital Mortality |
| url | http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0034-89102021000100236&tlng=en |
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