Sulpiride stimulation of prolactin secretion in adolescents with gynecomastia: relation to the circulating levels of estradiol.
Basal levels of prolactin (PRL) and estradiol (E2) were studied in 10 adolescents with gynecomastia who were at stages II to IV of their sexual development. In 7 of the 10 patients, the hypophyseal response of PRL to the administration of sulpiride was assessed: 5 of the 7 received 25 mg i.m., and...
| Main Authors: | , , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
Ordem dos Médicos
1980-08-01
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| Series: | Acta Médica Portuguesa |
| Online Access: | https://www.actamedicaportuguesa.com/revista/index.php/amp/article/view/4170 |
| _version_ | 1797996840354840576 |
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| author | Hugo L. Fideleff Silvia Belma Abraham Guitelman Ana Maria Baigorri Daniel Aquilano Hugo E. Scaglia |
| author_facet | Hugo L. Fideleff Silvia Belma Abraham Guitelman Ana Maria Baigorri Daniel Aquilano Hugo E. Scaglia |
| author_sort | Hugo L. Fideleff |
| collection | DOAJ |
| description |
Basal levels of prolactin (PRL) and estradiol (E2) were studied in 10 adolescents with gynecomastia who were at stages II to IV of their sexual development. In 7 of the 10 patients, the hypophyseal response of PRL to the administration of sulpiride was assessed: 5 of the 7 received 25 mg i.m., and the remaining 50 mg. i.m. The 10 cases were compared with 12 control boys without gynecomastia matched for stage of sexual development. Five of the controls were given 25 mg of sulpiride i.m. and the other 50 mg. Basal PRL levels were the same in both groups. Sulpiride stimulates the secretion of PRL in boys with and without gynecomastia. However, a significantly increased circulating E2 level was found in patients with gynecomastia.
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| first_indexed | 2024-04-11T10:23:53Z |
| format | Article |
| id | doaj.art-8263ccdce12440dea4d031d7db92b992 |
| institution | Directory Open Access Journal |
| issn | 0870-399X 1646-0758 |
| language | English |
| last_indexed | 2024-04-11T10:23:53Z |
| publishDate | 1980-08-01 |
| publisher | Ordem dos Médicos |
| record_format | Article |
| series | Acta Médica Portuguesa |
| spelling | doaj.art-8263ccdce12440dea4d031d7db92b9922022-12-22T04:29:39ZengOrdem dos MédicosActa Médica Portuguesa0870-399X1646-07581980-08-012410.20344/amp.4170Sulpiride stimulation of prolactin secretion in adolescents with gynecomastia: relation to the circulating levels of estradiol.Hugo L. Fideleff0Silvia Belma1Abraham Guitelman2Ana Maria Baigorri3Daniel Aquilano4Hugo E. Scaglia5Unidad endocrinologia, Hospital Dr. T. Alvarez, Buenos Aires y Centro de Referencia de RIA. Distrito 1 de ia Federacion Bioquimica de ia Provincia de Buenos Aires. La Plata. Argentina.Unidad endocrinologia, Hospital Dr. T. Alvarez, Buenos Aires y Centro de Referencia de RIA. Distrito 1 de ia Federacion Bioquimica de ia Provincia de Buenos Aires. La Plata. Argentina.Unidad endocrinologia, Hospital Dr. T. Alvarez, Buenos Aires y Centro de Referencia de RIA. Distrito 1 de ia Federacion Bioquimica de ia Provincia de Buenos Aires. La Plata. Argentina.Unidad endocrinologia, Hospital Dr. T. Alvarez, Buenos Aires y Centro de Referencia de RIA. Distrito 1 de ia Federacion Bioquimica de ia Provincia de Buenos Aires. La Plata. Argentina.Unidad endocrinologia, Hospital Dr. T. Alvarez, Buenos Aires y Centro de Referencia de RIA. Distrito 1 de ia Federacion Bioquimica de ia Provincia de Buenos Aires. La Plata. Argentina.Unidad endocrinologia, Hospital Dr. T. Alvarez, Buenos Aires y Centro de Referencia de RIA. Distrito 1 de ia Federacion Bioquimica de ia Provincia de Buenos Aires. La Plata. Argentina. Basal levels of prolactin (PRL) and estradiol (E2) were studied in 10 adolescents with gynecomastia who were at stages II to IV of their sexual development. In 7 of the 10 patients, the hypophyseal response of PRL to the administration of sulpiride was assessed: 5 of the 7 received 25 mg i.m., and the remaining 50 mg. i.m. The 10 cases were compared with 12 control boys without gynecomastia matched for stage of sexual development. Five of the controls were given 25 mg of sulpiride i.m. and the other 50 mg. Basal PRL levels were the same in both groups. Sulpiride stimulates the secretion of PRL in boys with and without gynecomastia. However, a significantly increased circulating E2 level was found in patients with gynecomastia. https://www.actamedicaportuguesa.com/revista/index.php/amp/article/view/4170 |
| spellingShingle | Hugo L. Fideleff Silvia Belma Abraham Guitelman Ana Maria Baigorri Daniel Aquilano Hugo E. Scaglia Sulpiride stimulation of prolactin secretion in adolescents with gynecomastia: relation to the circulating levels of estradiol. Acta Médica Portuguesa |
| title | Sulpiride stimulation of prolactin secretion in adolescents with gynecomastia: relation to the circulating levels of estradiol. |
| title_full | Sulpiride stimulation of prolactin secretion in adolescents with gynecomastia: relation to the circulating levels of estradiol. |
| title_fullStr | Sulpiride stimulation of prolactin secretion in adolescents with gynecomastia: relation to the circulating levels of estradiol. |
| title_full_unstemmed | Sulpiride stimulation of prolactin secretion in adolescents with gynecomastia: relation to the circulating levels of estradiol. |
| title_short | Sulpiride stimulation of prolactin secretion in adolescents with gynecomastia: relation to the circulating levels of estradiol. |
| title_sort | sulpiride stimulation of prolactin secretion in adolescents with gynecomastia relation to the circulating levels of estradiol |
| url | https://www.actamedicaportuguesa.com/revista/index.php/amp/article/view/4170 |
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