Maresin1 Ameliorates Sepsis-Induced Microglial Neuritis Induced through Blocking TLR4-NF-κ B-NLRP3 Signaling Pathway

Maresin1 Ameliorates Sepsis-Induced Microglial Neuritis Induced through Blocking TLR4-NF-κ B-NLRP3 Signaling Pathway

<b>Objective</b>: Neuroinflammation is a major etiology of cognitive dysfunction due to sepsis. Maresin1 (MaR1), identified as a docosahexaenoic acid (DHA)-derived metabolite from macrophages, has been demonstrated to exhibit potent neuroprotective and anti-inflammatory effects. Neverthe...

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Bibliographic Details
Main Authors: Huiping Wu, Ying Wang, Haiyan Fu, Lili Ji, Na Li, Dan Zhang, Longxiang Su, Zhansheng Hu
Format: Article
Language:English
Published: MDPI AG 2023-03-01
Series:Journal of Personalized Medicine
Subjects:
sepsis
microglia
Maresin1 (MaR1)
TLR4-NF-κB
NLRP3 inflammasome
Online Access:https://www.mdpi.com/2075-4426/13/3/534

Internet

https://www.mdpi.com/2075-4426/13/3/534

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