De-obstruction of bladder outlet in humans reverses organ remodelling by normalizing the expression of key transcription factors

De-obstruction of bladder outlet in humans reverses organ remodelling by normalizing the expression of key transcription factors

Abstract Background Benign prostatic hyperplasia in elderly males often causes bladder outlet obstruction termed benign prostatic obstruction (BPO). BPO induces lower urinary tract symptoms and quantifiable urodynamic alterations in bladder function. When conservative medical treatments are exhauste...

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Bibliographic Details
Main Authors: Akshay Akshay, Ali Hashemi Gheinani, Mustafa Besic, Sophie Braga, Anne-Christine Uldry, Manfred Heller, Hubert Rehrauer, Catharine Aquino Fournier, Fiona C. Burkhard, Katia Monastyrskaya
Format: Article
Language:English
Published: BMC 2024-02-01
Series:BMC Urology
Subjects:
Bladder
Obstruction
Gene expression
Urodynamics
Omics
Online Access:https://doi.org/10.1186/s12894-024-01417-8

Internet

https://doi.org/10.1186/s12894-024-01417-8

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