De-obstruction of bladder outlet in humans reverses organ remodelling by normalizing the expression of key transcription factors
Abstract Background Benign prostatic hyperplasia in elderly males often causes bladder outlet obstruction termed benign prostatic obstruction (BPO). BPO induces lower urinary tract symptoms and quantifiable urodynamic alterations in bladder function. When conservative medical treatments are exhauste...
Main Authors: | Akshay Akshay, Ali Hashemi Gheinani, Mustafa Besic, Sophie Braga, Anne-Christine Uldry, Manfred Heller, Hubert Rehrauer, Catharine Aquino Fournier, Fiona C. Burkhard, Katia Monastyrskaya |
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Format: | Article |
Language: | English |
Published: |
BMC
2024-02-01
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Series: | BMC Urology |
Subjects: | |
Online Access: | https://doi.org/10.1186/s12894-024-01417-8 |
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