Synthesis and Evaluation of Anti-acetylcholinesterase Activity of 2-(2-(4-(2-Oxo-2-phenylethyl)piperazin-1-yl) ethyl)Isoindoline-1,3-dione Derivatives with Potential Anti-Alzheimer Effects

Synthesis and Evaluation of Anti-acetylcholinesterase Activity of 2-(2-(4-(2-Oxo-2-phenylethyl)piperazin-1-yl) ethyl)Isoindoline-1,3-dione Derivatives with Potential Anti-Alzheimer Effects

Objective(s): Alzheimer's disease (AD) is a neurodegenerative disorder in elderly patients. Decrease in cholinergic neurotransmission is the main known cause in the pathophysiology of the disease. Improvement and potentiation of the cholinergic system could be beneficial for treatment of the AD...

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Bibliographic Details
Main Authors:	Alireza Aliabadi, Alireza Foroumadi, Ahmad Mohammadi-Farani, Mahdi Garmsiri Mahvar
Format:	Article
Language:	English
Published:	Mashhad University of Medical Sciences 2013-10-01
Series:	Iranian Journal of Basic Medical Sciences
Subjects:	Acetylcholinesterase Alzheimer Phthalimide Synthesis
Online Access:	http://ijbms.mums.ac.ir/pdf_1866_c35e303ca75b2ff194e595de6dd9cad3.html

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