Downregulation of miR-22 Contributes to Epithelial-Mesenchymal Transition in Osteosarcoma by Targeting Twist1

Downregulation of miR-22 Contributes to Epithelial-Mesenchymal Transition in Osteosarcoma by Targeting Twist1

The epithelial-mesenchymal transition (EMT) is a vital step in osteosarcoma (OS) progression toward metastasis, but the specific molecular events governing this process are incompletely characterized, with miRNAs having increasingly been found to regulate the EMT. In this study, We assessed levels o...

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Bibliographic Details
Main Authors: Shu-tao Zhu, Xiao Wang, Jun-yi Wang, Guang-hui Xi, Yang Liu
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-04-01
Series:Frontiers in Oncology
Subjects:
miR-22
EMT
metastasis
twist1
osteosarcoma
Online Access:https://www.frontiersin.org/article/10.3389/fonc.2020.00406/full

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