Study of antibacterial effect of the extracts of the sea cucumber (Holothuria leucospilota) of Persian Gulf on the Escherichia coli
Background and Aim: Sea cucumber has different properties through having different biological compounds. In this study, the antibacterial activity of the extracts of the sea cucumber Holothuria leucospilota was investigated on Escherichia coli. Materials and Methods: Sea cucumber fishery samples af...
| Main Authors: | , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
Farname
2014-06-01
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| Series: | Iranian Journal of Medical Microbiology |
| Subjects: | |
| Online Access: | http://www.ijmm.ir/browse.php?a_code=A-10-177-1&slc_lang=en&sid=1 |
| Summary: | Background
and Aim: Sea cucumber has different properties
through having different biological compounds. In this study, the antibacterial
activity of the extracts of the sea cucumber Holothuria leucospilota was
investigated on Escherichia coli.
Materials
and Methods: Sea cucumber
fishery samples after washing were crushed and powdered. The methanol,
chloroform and hexane extracts of body wall, gonads and intestine were
prepared. The antibacterial effect of the extracts was studied on the Escherichia
coli at several concentrations. Also minimum inhibitory concentration and
minimum bactericidal concentration of the extracts were studied against
bacteria.
Results:
The results showed that methanol
extracts had no effect, chloroform extracts showed antibacterial activity at
concentrations of 5 and 10 mg per ml. Hexane extract of wall at concentrations
of 5 and 10 and the intestine hexane extract at a concentration of 2.5, 5 and
10 mg per ml have antibacterial activity against bacteria. None of the
concentrations of the gonadal hexane extract showed any antibacterial activity. Only the
hexane extract of intestine killed the bacteria at a concentration of 10 mg
/ml.
Conclusions:
According to the findings of this
research, extracts of sea cucumber Holothuria leucospilota can be used in preparation of natural antimicrobial drugs as a
valuable source of compounds with potential of antibacterial. |
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| ISSN: | 1735-8612 2345-4342 |