The prevalence of psychiatric disorders in patients with Multiple Sclerosis in Saudi Arabia: A cross-sectional multi-centered study
Introduction Multiple sclerosis is considered one of the leading causes of neurological non-traumatic disability among young people. Given the chronic progressive nature of the disease, psychiatric disorders are more prevalent among those patients as reported in the literature; however, the data in...
| Main Authors: | , , , , , , , , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
Cambridge University Press
2023-03-01
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| Series: | European Psychiatry |
| Online Access: | https://www.cambridge.org/core/product/identifier/S0924933823018370/type/journal_article |
| _version_ | 1827753858280980480 |
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| author | A. Alserihi A. Alswat B. Altirkistani O. Baeshen E. Alrushid J. Alkhudair O. Wadaan A. Aldbas A. Alsaleh Y. Al Malik A. Abulaban S. Makkawi |
| author_facet | A. Alserihi A. Alswat B. Altirkistani O. Baeshen E. Alrushid J. Alkhudair O. Wadaan A. Aldbas A. Alsaleh Y. Al Malik A. Abulaban S. Makkawi |
| author_sort | A. Alserihi |
| collection | DOAJ |
| description |
Introduction
Multiple sclerosis is considered one of the leading causes of neurological non-traumatic disability among young people. Given the chronic progressive nature of the disease, psychiatric disorders are more prevalent among those patients as reported in the literature; however, the data in Saudi Arabia is lacking.
Objectives
The study aimed to estimate the prevalence of psychiatric disorders among MS patient in Saudi Arabia.
Methods
This was a cross-sectional multi-centered study, including patients with multiple sclerosis. Participants were interviewed and asked to fill a validated survey that consisted of demographics, Patient Health Questionnaire-9 (PHQ-9), and Generalized Anxiety Disorder-7 (GAD-7) questionnaire. Descriptive statistics were performed, and the analysis were made using Chi-square, Fisher’s exact, and ANOVA tests as appropriate.
Results
A total of 192 participants were included in the study. Based on a cutoff score of > 10 in the GAD-7 and PHQ-9 scales, the prevalence of anxiety was 26.1% (n-50), with majority of the participants having minimal anxiety (40%); meanwhile, the prevalence of depression was 42.7% (n=82), and most of them had mild depression (30%). [table 1, image 1 and 2] Females participants significantly scored higher in GAD-7 and PHQ-9 compared to males (p-value= 0.0376 and 0.1134, respectively). [table 2 and 3] In addition, no significant association was detected between functional disability (EDSS score) and the prevalence of anxiety and depression.table 1
Items
GAD 7 score, Mean (SD)
6.5 (±4.9)
GAD 7, N (%)
Fit for Anxiety (>10) *
50 (26%)
Not Fit for Anxiety (<10) *
142 (74%)
PHQ 9 score, Mean (SD)
8.8 (±6.1)
PHQ 9, N (%)
Fit for Depression (>10) *
82 (42.7%)
Not Fit for Depression (<10) *
110 (57.3%)
table 2
Fit for Anxiety (n=50)
Not Fit for Anxiety (n=142)
P Value
Gender, N (%)
- Male
10 (20%)
51 (35.9%)
0.0376
- Female
40 (80%)
91 (64.1%)
table 3
N(%)
Fit for Depression (n=82)
Not Fit for Depression (n=110)
P Value
Gender, N (%)
- Male
21 (25.6%)
40 (36.4%)
0.1134
- Female
61 (74.4%)
70 (63.6%)
Image:
Image 2:
Conclusions
This study reported high level of anxiety and depression among MS patients, with females being more affected. Since these co-morbid disorders could affect the disease course negatively, screening is of paramount significance.
Disclosure of Interest
None Declared |
| first_indexed | 2024-03-11T07:41:16Z |
| format | Article |
| id | doaj.art-826f0fa1cfca46c29baa9585bfc286c2 |
| institution | Directory Open Access Journal |
| issn | 0924-9338 1778-3585 |
| language | English |
| last_indexed | 2024-03-11T07:41:16Z |
| publishDate | 2023-03-01 |
| publisher | Cambridge University Press |
| record_format | Article |
| series | European Psychiatry |
| spelling | doaj.art-826f0fa1cfca46c29baa9585bfc286c22023-11-17T05:08:30ZengCambridge University PressEuropean Psychiatry0924-93381778-35852023-03-0166S867S86810.1192/j.eurpsy.2023.1837The prevalence of psychiatric disorders in patients with Multiple Sclerosis in Saudi Arabia: A cross-sectional multi-centered studyA. Alserihi0A. Alswat1B. Altirkistani2O. Baeshen3E. Alrushid4J. Alkhudair5O. Wadaan6A. Aldbas7A. Alsaleh8Y. Al Malik9A. Abulaban10S. Makkawi11College of Medicine, king Saud bin Abdulaziz University for Health SciencesCollege of Medicine, king Saud bin Abdulaziz University for Health SciencesCollege of Medicine, king Saud bin Abdulaziz University for Health Sciences, Jeddah, Saudi Arabia, JeddahCollege of Medicine, king Saud bin Abdulaziz University for Health SciencesCollege of Medicine, king Saud bin Abdulaziz University for Health SciencesCollege of Medicine, king Saud bin Abdulaziz University for Health SciencesCollege of Medicine, king Saud bin Abdulaziz University for Health SciencesDepartment of Medicine, King Abdulaziz Medical City, National Guard Health Affairs, RiyadhDepartment of Medicine, King Abdulaziz Medical City, National Guard Health Affairs, Jeddah, Saudi ArabiaDepartment of Medicine, King Abdulaziz Medical City, National Guard Health Affairs, RiyadhDepartment of Medicine, King Abdulaziz Medical City, National Guard Health Affairs, RiyadhDepartment of Medicine, King Abdulaziz Medical City, National Guard Health Affairs, Jeddah, Saudi Arabia Introduction Multiple sclerosis is considered one of the leading causes of neurological non-traumatic disability among young people. Given the chronic progressive nature of the disease, psychiatric disorders are more prevalent among those patients as reported in the literature; however, the data in Saudi Arabia is lacking. Objectives The study aimed to estimate the prevalence of psychiatric disorders among MS patient in Saudi Arabia. Methods This was a cross-sectional multi-centered study, including patients with multiple sclerosis. Participants were interviewed and asked to fill a validated survey that consisted of demographics, Patient Health Questionnaire-9 (PHQ-9), and Generalized Anxiety Disorder-7 (GAD-7) questionnaire. Descriptive statistics were performed, and the analysis were made using Chi-square, Fisher’s exact, and ANOVA tests as appropriate. Results A total of 192 participants were included in the study. Based on a cutoff score of > 10 in the GAD-7 and PHQ-9 scales, the prevalence of anxiety was 26.1% (n-50), with majority of the participants having minimal anxiety (40%); meanwhile, the prevalence of depression was 42.7% (n=82), and most of them had mild depression (30%). [table 1, image 1 and 2] Females participants significantly scored higher in GAD-7 and PHQ-9 compared to males (p-value= 0.0376 and 0.1134, respectively). [table 2 and 3] In addition, no significant association was detected between functional disability (EDSS score) and the prevalence of anxiety and depression.table 1 Items GAD 7 score, Mean (SD) 6.5 (±4.9) GAD 7, N (%) Fit for Anxiety (>10) * 50 (26%) Not Fit for Anxiety (<10) * 142 (74%) PHQ 9 score, Mean (SD) 8.8 (±6.1) PHQ 9, N (%) Fit for Depression (>10) * 82 (42.7%) Not Fit for Depression (<10) * 110 (57.3%) table 2 Fit for Anxiety (n=50) Not Fit for Anxiety (n=142) P Value Gender, N (%) - Male 10 (20%) 51 (35.9%) 0.0376 - Female 40 (80%) 91 (64.1%) table 3 N(%) Fit for Depression (n=82) Not Fit for Depression (n=110) P Value Gender, N (%) - Male 21 (25.6%) 40 (36.4%) 0.1134 - Female 61 (74.4%) 70 (63.6%) Image: Image 2: Conclusions This study reported high level of anxiety and depression among MS patients, with females being more affected. Since these co-morbid disorders could affect the disease course negatively, screening is of paramount significance. Disclosure of Interest None Declaredhttps://www.cambridge.org/core/product/identifier/S0924933823018370/type/journal_article |
| spellingShingle | A. Alserihi A. Alswat B. Altirkistani O. Baeshen E. Alrushid J. Alkhudair O. Wadaan A. Aldbas A. Alsaleh Y. Al Malik A. Abulaban S. Makkawi The prevalence of psychiatric disorders in patients with Multiple Sclerosis in Saudi Arabia: A cross-sectional multi-centered study European Psychiatry |
| title | The prevalence of psychiatric disorders in patients with Multiple Sclerosis in Saudi Arabia: A cross-sectional multi-centered study |
| title_full | The prevalence of psychiatric disorders in patients with Multiple Sclerosis in Saudi Arabia: A cross-sectional multi-centered study |
| title_fullStr | The prevalence of psychiatric disorders in patients with Multiple Sclerosis in Saudi Arabia: A cross-sectional multi-centered study |
| title_full_unstemmed | The prevalence of psychiatric disorders in patients with Multiple Sclerosis in Saudi Arabia: A cross-sectional multi-centered study |
| title_short | The prevalence of psychiatric disorders in patients with Multiple Sclerosis in Saudi Arabia: A cross-sectional multi-centered study |
| title_sort | prevalence of psychiatric disorders in patients with multiple sclerosis in saudi arabia a cross sectional multi centered study |
| url | https://www.cambridge.org/core/product/identifier/S0924933823018370/type/journal_article |
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