Cerebral mGluR5 availability contributes to elevated sleep need and behavioral adjustment after sleep deprivation
Increased sleep time and intensity quantified as low-frequency brain electrical activity after sleep loss demonstrate that sleep need is homeostatically regulated, yet the underlying molecular mechanisms remain elusive. We here demonstrate that metabotropic glutamate receptors of subtype 5 (mGluR5)...
Main Authors: | Sebastian C Holst, Alexandra Sousek, Katharina Hefti, Sohrab Saberi-Moghadam, Alfred Buck, Simon M Ametamey, Milan Scheidegger, Paul Franken, Anke Henning, Erich Seifritz, Mehdi Tafti, Hans-Peter Landolt |
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Format: | Article |
Language: | English |
Published: |
eLife Sciences Publications Ltd
2017-10-01
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Series: | eLife |
Subjects: | |
Online Access: | https://elifesciences.org/articles/28751 |
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