The dark side of paclitaxel
The bark extract of Pacific Yew (Taxus brevifolia) was first reported to have anti-tumor activity in 1963. The active constituent responsible for this activity was later identified in 1971 as paclitaxel [1]. Paclitaxel is a cytotoxic drug used in the treatment of variety of tumors including ovarian,...
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| Format: | Article |
| Language: | English |
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Frontiers Media S.A.
2011-12-01
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| Series: | Oncology Reviews |
| Online Access: | http://www.oncologyreviews.org/index.php/or/article/view/50 |
| _version_ | 1828073113626083328 |
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| author | Alekha K. Dash |
| author_facet | Alekha K. Dash |
| author_sort | Alekha K. Dash |
| collection | DOAJ |
| description | The bark extract of Pacific Yew (Taxus brevifolia) was first reported to have anti-tumor activity in 1963. The active constituent responsible for this activity was later identified in 1971 as paclitaxel [1]. Paclitaxel is a cytotoxic drug used in the treatment of variety of tumors including ovarian, breast, and non-small-cell lung cancers... |
| first_indexed | 2024-04-11T01:22:51Z |
| format | Article |
| id | doaj.art-82716440e23140d1b45e2d74ae5ee537 |
| institution | Directory Open Access Journal |
| issn | 1970-5557 1970-5565 |
| language | English |
| last_indexed | 2024-04-11T01:22:51Z |
| publishDate | 2011-12-01 |
| publisher | Frontiers Media S.A. |
| record_format | Article |
| series | Oncology Reviews |
| spelling | doaj.art-82716440e23140d1b45e2d74ae5ee5372023-01-03T11:00:16ZengFrontiers Media S.A.Oncology Reviews1970-55571970-55652011-12-014210.4081/oncol.2010.7145The dark side of paclitaxelAlekha K. Dash0Department of Pharmacy Sciences, School of Pharmacy and Health Professions, Creighton University, OmahaThe bark extract of Pacific Yew (Taxus brevifolia) was first reported to have anti-tumor activity in 1963. The active constituent responsible for this activity was later identified in 1971 as paclitaxel [1]. Paclitaxel is a cytotoxic drug used in the treatment of variety of tumors including ovarian, breast, and non-small-cell lung cancers...http://www.oncologyreviews.org/index.php/or/article/view/50 |
| spellingShingle | Alekha K. Dash The dark side of paclitaxel Oncology Reviews |
| title | The dark side of paclitaxel |
| title_full | The dark side of paclitaxel |
| title_fullStr | The dark side of paclitaxel |
| title_full_unstemmed | The dark side of paclitaxel |
| title_short | The dark side of paclitaxel |
| title_sort | dark side of paclitaxel |
| url | http://www.oncologyreviews.org/index.php/or/article/view/50 |
| work_keys_str_mv | AT alekhakdash thedarksideofpaclitaxel AT alekhakdash darksideofpaclitaxel |