Cold plasma copolymer with antimicrobial activity deposited on three different substrates
Abstract A good strategy to prevent early deposition of bacteria that can form biofilms is the application of antimicrobial coatings to existing surfaces, however this field has been little explored and coatings are often non uniform in thickness. A homogeneous film of R-Carvone-Octadiene (ppCop) wa...
| Main Authors: | , , , , , , , , , , , |
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| Format: | Article |
| Language: | English |
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Associação Brasileira de Polímeros
2023-12-01
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| Series: | Polímeros |
| Subjects: | |
| Online Access: | http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0104-14282023000400402&tlng=en |
| _version_ | 1797375589520244736 |
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| author | Erick Osvaldo Martínez Ruiz Xi Rao Abril Fonseca García Carlos Gallardo Vega Carmen Natividad Alvarado Canche José Abraham Gonzáles López Antonio Serguei Ledezma Pérez Miriam Desiree Davila Medina Claudia Gabriela Cuellar Gaona Rosa Idalia Narro Céspedes Gustavo Soria Arguello María Guadalupe Neira Velázquez |
| author_facet | Erick Osvaldo Martínez Ruiz Xi Rao Abril Fonseca García Carlos Gallardo Vega Carmen Natividad Alvarado Canche José Abraham Gonzáles López Antonio Serguei Ledezma Pérez Miriam Desiree Davila Medina Claudia Gabriela Cuellar Gaona Rosa Idalia Narro Céspedes Gustavo Soria Arguello María Guadalupe Neira Velázquez |
| author_sort | Erick Osvaldo Martínez Ruiz |
| collection | DOAJ |
| description | Abstract A good strategy to prevent early deposition of bacteria that can form biofilms is the application of antimicrobial coatings to existing surfaces, however this field has been little explored and coatings are often non uniform in thickness. A homogeneous film of R-Carvone-Octadiene (ppCop) was deposited on different substrates (coverslip, minced coverslip and fabric) by cold plasma copolymerization to study the influence of the substrate on antimicrobial activity and show clues about the influence of octadiene on copolymerization. The ppCop showed better antimicrobial activity results on the substrate with higher effective contact area, highlighting the influence of this variable on antimicrobial activity. The ppCop deposited on minced coverslip showed an inhibition of E. coli and S. aureus bacteria by 48.69 ±0.08% and 49.31 ±0.58% respectively, with an average roughness of 14.1±0.02 nm and a static water contact angle of 79± 0.4°. The ppCop showed no cytotoxicity to the human cell line. |
| first_indexed | 2024-03-08T19:26:35Z |
| format | Article |
| id | doaj.art-827457256816429a85cca1dd6dcdeb3d |
| institution | Directory Open Access Journal |
| issn | 1678-5169 |
| language | English |
| last_indexed | 2024-03-08T19:26:35Z |
| publishDate | 2023-12-01 |
| publisher | Associação Brasileira de Polímeros |
| record_format | Article |
| series | Polímeros |
| spelling | doaj.art-827457256816429a85cca1dd6dcdeb3d2023-12-26T08:27:50ZengAssociação Brasileira de PolímerosPolímeros1678-51692023-12-0133410.1590/0104-1428.20220099Cold plasma copolymer with antimicrobial activity deposited on three different substratesErick Osvaldo Martínez Ruizhttps://orcid.org/0000-0003-4276-8627Xi Raohttps://orcid.org/0000-0002-8159-8002Abril Fonseca Garcíahttps://orcid.org/0000-0002-7320-7796Carlos Gallardo Vegahttps://orcid.org/0000-0002-9602-8459Carmen Natividad Alvarado Canchehttps://orcid.org/0000-0002-9139-7239José Abraham Gonzáles Lópezhttps://orcid.org/0000-0002-9022-0618Antonio Serguei Ledezma Pérezhttps://orcid.org/0000-0003-0549-0208Miriam Desiree Davila Medinahttps://orcid.org/0000-0001-8897-0375Claudia Gabriela Cuellar Gaonahttps://orcid.org/0000-0002-1173-0055Rosa Idalia Narro Céspedeshttps://orcid.org/0000-0002-3559-1520Gustavo Soria Arguellohttps://orcid.org/0000-0002-9771-8638María Guadalupe Neira Velázquezhttps://orcid.org/0000-0002-3850-850XAbstract A good strategy to prevent early deposition of bacteria that can form biofilms is the application of antimicrobial coatings to existing surfaces, however this field has been little explored and coatings are often non uniform in thickness. A homogeneous film of R-Carvone-Octadiene (ppCop) was deposited on different substrates (coverslip, minced coverslip and fabric) by cold plasma copolymerization to study the influence of the substrate on antimicrobial activity and show clues about the influence of octadiene on copolymerization. The ppCop showed better antimicrobial activity results on the substrate with higher effective contact area, highlighting the influence of this variable on antimicrobial activity. The ppCop deposited on minced coverslip showed an inhibition of E. coli and S. aureus bacteria by 48.69 ±0.08% and 49.31 ±0.58% respectively, with an average roughness of 14.1±0.02 nm and a static water contact angle of 79± 0.4°. The ppCop showed no cytotoxicity to the human cell line.http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0104-14282023000400402&tlng=enantimicrobialbiofilmoctadieneplasmaR-Carvone |
| spellingShingle | Erick Osvaldo Martínez Ruiz Xi Rao Abril Fonseca García Carlos Gallardo Vega Carmen Natividad Alvarado Canche José Abraham Gonzáles López Antonio Serguei Ledezma Pérez Miriam Desiree Davila Medina Claudia Gabriela Cuellar Gaona Rosa Idalia Narro Céspedes Gustavo Soria Arguello María Guadalupe Neira Velázquez Cold plasma copolymer with antimicrobial activity deposited on three different substrates Polímeros antimicrobial biofilm octadiene plasma R-Carvone |
| title | Cold plasma copolymer with antimicrobial activity deposited on three different substrates |
| title_full | Cold plasma copolymer with antimicrobial activity deposited on three different substrates |
| title_fullStr | Cold plasma copolymer with antimicrobial activity deposited on three different substrates |
| title_full_unstemmed | Cold plasma copolymer with antimicrobial activity deposited on three different substrates |
| title_short | Cold plasma copolymer with antimicrobial activity deposited on three different substrates |
| title_sort | cold plasma copolymer with antimicrobial activity deposited on three different substrates |
| topic | antimicrobial biofilm octadiene plasma R-Carvone |
| url | http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0104-14282023000400402&tlng=en |
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