Effect of Binding Linkers on the Efficiency and Metabolite Profile of Biomimetic Reactions Catalyzed by Immobilized Metalloporphyrin

The investigation of liver-related metabolic stability of a drug candidate is a widely used key strategy in early-stage drug discovery. Metalloporphyrin-based biomimetic catalysts are good and well-described models of the function of CyP450 in hepatocytes. In this research, the immobilization of an...

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Bibliographic Details
Main Authors:	György T. Balogh, Balázs Decsi, Réka Krammer, Balázs Kenéz, Ferenc Ender, Tamás Hergert, Diána Balogh-Weiser
Format:	Article
Language:	English
Published:	MDPI AG 2022-12-01
Series:	Metabolites
Subjects:	biomimicking drug metabolism metalloporphyirin chloroquine immobilized catalyst nanoporous carrier
Online Access:	https://www.mdpi.com/2218-1989/12/12/1269

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