The prevalence and bacterial distribution of peritonitis amongst adults undergoing continuous ambulatory peritoneal dialysis at Universitas hospital
Background: Peritonitis is the leading cause of morbidity and technique failure in peritoneal dialysis (PD) patients. The International Society for Peritoneal Dialysis (ISPD) recommends each centre to monitor the peritonitis rates and the causative organisms in order to guide local empiric antibioti...
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| Format: | Article |
| Language: | English |
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AOSIS
2020-03-01
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| Series: | Southern African Journal of Infectious Diseases |
| Subjects: | |
| Online Access: | https://sajid.co.za/index.php/sajid/article/view/104 |
| _version_ | 1811312844212273152 |
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| author | Jolly Musoke Feziwe Bisiwe Akhil Natverlal Ilyas Moola Yusuf Moola Umar Kajee Antonio Parlato Andrea Bailey Jerome Arendse |
| author_facet | Jolly Musoke Feziwe Bisiwe Akhil Natverlal Ilyas Moola Yusuf Moola Umar Kajee Antonio Parlato Andrea Bailey Jerome Arendse |
| author_sort | Jolly Musoke |
| collection | DOAJ |
| description | Background: Peritonitis is the leading cause of morbidity and technique failure in peritoneal dialysis (PD) patients. The International Society for Peritoneal Dialysis (ISPD) recommends each centre to monitor the peritonitis rates and the causative organisms in order to guide local empiric antibiotic protocols. The aim of this study was to report on the peritonitis rates and describe the causative microorganisms and the antibiotic susceptibility in continuous ambulatory peritoneal dialysis (CAPD) adult patients at the Universitas Academic Hospital.
Methods: A single-centre, retrospective descriptive survey was conducted to determine the peritonitis rates in PD patients (January–December 2016). All CAPD patients aged ≥18 years, who presented with clinical features of PD-associated peritonitis, were included. The peritonitis episodes were studied per patient, and the causative microorganisms and the antibiotic susceptibility of the organisms were described.
Results: One hundred and twenty-eight patients underwent CAPD. The peritonitis rate was 1.45 episodes per year at risk. The prevalence of CAPD patients affected by at least one episode of CAPD-associated peritonitis during 2016 was 56.3%. The majority of episodes (76.7%) (n = 122) were mono-microbial. Gram-positive organisms accounted for 73.0% (n = 116) of the peritonitis episodes, coagulase-negative Staphylococcus being the most common. Gram-negative organisms accounted for 15.7% (n = 25) of the peritonitis episodes, and the common pathogens was Enterobacteriaceae.
Conclusion: The peritonitis rate was alarmingly high, with 1.45 episodes per year at risk; this is three times more than the recommended 0.5 episodes per year according to the ISPD guidelines. The culture-negative rate of 8.8% is within ISPD-acceptable limits. There is a need to strengthen preventive measures with regard to peritonitis. |
| first_indexed | 2024-04-13T10:43:41Z |
| format | Article |
| id | doaj.art-8276cb6b5f2a48df83df14bc2b7c7394 |
| institution | Directory Open Access Journal |
| issn | 2312-0053 2313-1810 |
| language | English |
| last_indexed | 2024-04-13T10:43:41Z |
| publishDate | 2020-03-01 |
| publisher | AOSIS |
| record_format | Article |
| series | Southern African Journal of Infectious Diseases |
| spelling | doaj.art-8276cb6b5f2a48df83df14bc2b7c73942022-12-22T02:49:51ZengAOSISSouthern African Journal of Infectious Diseases2312-00532313-18102020-03-01351e1e510.4102/sajid.v35i1.104137The prevalence and bacterial distribution of peritonitis amongst adults undergoing continuous ambulatory peritoneal dialysis at Universitas hospitalJolly Musoke0Feziwe Bisiwe1Akhil Natverlal2Ilyas Moola3Yusuf Moola4Umar Kajee5Antonio Parlato6Andrea Bailey7Jerome Arendse8Department of Medical Microbiology, Faculty of Health Sciences, University of the Free State, BloemfonteinDepartment of Internal Medicine, Faculty of Health Sciences, University of the Free State, BloemfonteinDepartment of Biostatistics, Faculty of Health Sciences, University of the Free State, BloemfonteinDepartment of Biostatistics, Faculty of Health Sciences, University of the Free State, BloemfonteinDepartment of Biostatistics, Faculty of Health Sciences, University of the Free State, BloemfonteinDepartment of Biostatistics, Faculty of Health Sciences, University of the Free State, BloemfonteinDepartment of Biostatistics, Faculty of Health Sciences, University of the Free State, BloemfonteinDepartment of Biostatistics, Faculty of Health Sciences, University of the Free State, BloemfonteinDepartment of Medical Microbiology, Faculty of Health Sciences, University of the Free State, BloemfonteinBackground: Peritonitis is the leading cause of morbidity and technique failure in peritoneal dialysis (PD) patients. The International Society for Peritoneal Dialysis (ISPD) recommends each centre to monitor the peritonitis rates and the causative organisms in order to guide local empiric antibiotic protocols. The aim of this study was to report on the peritonitis rates and describe the causative microorganisms and the antibiotic susceptibility in continuous ambulatory peritoneal dialysis (CAPD) adult patients at the Universitas Academic Hospital. Methods: A single-centre, retrospective descriptive survey was conducted to determine the peritonitis rates in PD patients (January–December 2016). All CAPD patients aged ≥18 years, who presented with clinical features of PD-associated peritonitis, were included. The peritonitis episodes were studied per patient, and the causative microorganisms and the antibiotic susceptibility of the organisms were described. Results: One hundred and twenty-eight patients underwent CAPD. The peritonitis rate was 1.45 episodes per year at risk. The prevalence of CAPD patients affected by at least one episode of CAPD-associated peritonitis during 2016 was 56.3%. The majority of episodes (76.7%) (n = 122) were mono-microbial. Gram-positive organisms accounted for 73.0% (n = 116) of the peritonitis episodes, coagulase-negative Staphylococcus being the most common. Gram-negative organisms accounted for 15.7% (n = 25) of the peritonitis episodes, and the common pathogens was Enterobacteriaceae. Conclusion: The peritonitis rate was alarmingly high, with 1.45 episodes per year at risk; this is three times more than the recommended 0.5 episodes per year according to the ISPD guidelines. The culture-negative rate of 8.8% is within ISPD-acceptable limits. There is a need to strengthen preventive measures with regard to peritonitis.https://sajid.co.za/index.php/sajid/article/view/104capd patientsperitonitisuniversitas academic hospitalbacterial distributionperitoneal dialysis. |
| spellingShingle | Jolly Musoke Feziwe Bisiwe Akhil Natverlal Ilyas Moola Yusuf Moola Umar Kajee Antonio Parlato Andrea Bailey Jerome Arendse The prevalence and bacterial distribution of peritonitis amongst adults undergoing continuous ambulatory peritoneal dialysis at Universitas hospital Southern African Journal of Infectious Diseases capd patients peritonitis universitas academic hospital bacterial distribution peritoneal dialysis. |
| title | The prevalence and bacterial distribution of peritonitis amongst adults undergoing continuous ambulatory peritoneal dialysis at Universitas hospital |
| title_full | The prevalence and bacterial distribution of peritonitis amongst adults undergoing continuous ambulatory peritoneal dialysis at Universitas hospital |
| title_fullStr | The prevalence and bacterial distribution of peritonitis amongst adults undergoing continuous ambulatory peritoneal dialysis at Universitas hospital |
| title_full_unstemmed | The prevalence and bacterial distribution of peritonitis amongst adults undergoing continuous ambulatory peritoneal dialysis at Universitas hospital |
| title_short | The prevalence and bacterial distribution of peritonitis amongst adults undergoing continuous ambulatory peritoneal dialysis at Universitas hospital |
| title_sort | prevalence and bacterial distribution of peritonitis amongst adults undergoing continuous ambulatory peritoneal dialysis at universitas hospital |
| topic | capd patients peritonitis universitas academic hospital bacterial distribution peritoneal dialysis. |
| url | https://sajid.co.za/index.php/sajid/article/view/104 |
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