Infectious diseases, comorbidities and outcomes in hospitalized people who inject drugs (PWID) infections in persons who inject drugs
Injection drug use poses a public health challenge. Clinical experience indicates that people who inject drugs (PWID) are hospitalized frequently for infectious diseases, but little is known about outcomes when admitted. Charts were identified from local hospitals between 2013–2018 using consultatio...
| Main Authors: | , , , , , , , , , , , , , , , , , |
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| Format: | Article |
| Language: | English |
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Public Library of Science (PLoS)
2022-01-01
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| Series: | PLoS ONE |
| Online Access: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9020696/?tool=EBI |
| _version_ | 1818278228349943808 |
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| author | Jacqueline Lim Sureka Pavalagantharajah Chris P Verschoor Eric Lentz Mark Loeb Mitchell Levine Marek Smieja Lawrence Mbuagbaw Dale Kalina Jean-Eric Tarride Tim O’Shea Anna Cvetkovic Sarah van Gaalen Aidan Reid Findlater Robin Lennox Carol Bassim Cynthia Lokker Elizabeth Alvarez |
| author_facet | Jacqueline Lim Sureka Pavalagantharajah Chris P Verschoor Eric Lentz Mark Loeb Mitchell Levine Marek Smieja Lawrence Mbuagbaw Dale Kalina Jean-Eric Tarride Tim O’Shea Anna Cvetkovic Sarah van Gaalen Aidan Reid Findlater Robin Lennox Carol Bassim Cynthia Lokker Elizabeth Alvarez |
| author_sort | Jacqueline Lim |
| collection | DOAJ |
| description | Injection drug use poses a public health challenge. Clinical experience indicates that people who inject drugs (PWID) are hospitalized frequently for infectious diseases, but little is known about outcomes when admitted. Charts were identified from local hospitals between 2013–2018 using consultation lists and hospital record searches. Included individuals injected drugs in the past six months and presented with infection. Charts were accessed using the hospital information system, undergoing primary and secondary reviews using Research Electronic Data Capture (REDCap). The Wilcoxon rank-sum test was used for comparisons between outcome categories. Categorical data were summarized as count and frequency, and compared using Fisher’s exact test. Of 240 individuals, 33% were admitted to the intensive care unit, 36% underwent surgery, 12% left against medical advice (AMA), and 9% died. Infectious diagnoses included bacteremia (31%), abscess (29%), endocarditis (29%), cellulitis (20%), sepsis (10%), osteomyelitis (9%), septic arthritis (8%), pneumonia (7%), discitis (2%), meningitis/encephalitis (2%), or other (7%). Sixty-six percent had stable housing and 60% had a family physician. Fifty-four percent of patient-initiated discharges were seen in the emergency department within 30 days and 29% were readmitted. PWID are at risk for infections. Understanding their healthcare trajectory is essential to improve their care. |
| first_indexed | 2024-12-12T23:14:06Z |
| format | Article |
| id | doaj.art-82796a56826b4f249cde57035821f098 |
| institution | Directory Open Access Journal |
| issn | 1932-6203 |
| language | English |
| last_indexed | 2024-12-12T23:14:06Z |
| publishDate | 2022-01-01 |
| publisher | Public Library of Science (PLoS) |
| record_format | Article |
| series | PLoS ONE |
| spelling | doaj.art-82796a56826b4f249cde57035821f0982022-12-22T00:08:31ZengPublic Library of Science (PLoS)PLoS ONE1932-62032022-01-01174Infectious diseases, comorbidities and outcomes in hospitalized people who inject drugs (PWID) infections in persons who inject drugsJacqueline LimSureka PavalagantharajahChris P VerschoorEric LentzMark LoebMitchell LevineMarek SmiejaLawrence MbuagbawDale KalinaJean-Eric TarrideTim O’SheaAnna CvetkovicSarah van GaalenAidan Reid FindlaterRobin LennoxCarol BassimCynthia LokkerElizabeth AlvarezInjection drug use poses a public health challenge. Clinical experience indicates that people who inject drugs (PWID) are hospitalized frequently for infectious diseases, but little is known about outcomes when admitted. Charts were identified from local hospitals between 2013–2018 using consultation lists and hospital record searches. Included individuals injected drugs in the past six months and presented with infection. Charts were accessed using the hospital information system, undergoing primary and secondary reviews using Research Electronic Data Capture (REDCap). The Wilcoxon rank-sum test was used for comparisons between outcome categories. Categorical data were summarized as count and frequency, and compared using Fisher’s exact test. Of 240 individuals, 33% were admitted to the intensive care unit, 36% underwent surgery, 12% left against medical advice (AMA), and 9% died. Infectious diagnoses included bacteremia (31%), abscess (29%), endocarditis (29%), cellulitis (20%), sepsis (10%), osteomyelitis (9%), septic arthritis (8%), pneumonia (7%), discitis (2%), meningitis/encephalitis (2%), or other (7%). Sixty-six percent had stable housing and 60% had a family physician. Fifty-four percent of patient-initiated discharges were seen in the emergency department within 30 days and 29% were readmitted. PWID are at risk for infections. Understanding their healthcare trajectory is essential to improve their care.https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9020696/?tool=EBI |
| spellingShingle | Jacqueline Lim Sureka Pavalagantharajah Chris P Verschoor Eric Lentz Mark Loeb Mitchell Levine Marek Smieja Lawrence Mbuagbaw Dale Kalina Jean-Eric Tarride Tim O’Shea Anna Cvetkovic Sarah van Gaalen Aidan Reid Findlater Robin Lennox Carol Bassim Cynthia Lokker Elizabeth Alvarez Infectious diseases, comorbidities and outcomes in hospitalized people who inject drugs (PWID) infections in persons who inject drugs PLoS ONE |
| title | Infectious diseases, comorbidities and outcomes in hospitalized people who inject drugs (PWID) infections in persons who inject drugs |
| title_full | Infectious diseases, comorbidities and outcomes in hospitalized people who inject drugs (PWID) infections in persons who inject drugs |
| title_fullStr | Infectious diseases, comorbidities and outcomes in hospitalized people who inject drugs (PWID) infections in persons who inject drugs |
| title_full_unstemmed | Infectious diseases, comorbidities and outcomes in hospitalized people who inject drugs (PWID) infections in persons who inject drugs |
| title_short | Infectious diseases, comorbidities and outcomes in hospitalized people who inject drugs (PWID) infections in persons who inject drugs |
| title_sort | infectious diseases comorbidities and outcomes in hospitalized people who inject drugs pwid infections in persons who inject drugs |
| url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9020696/?tool=EBI |
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